Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The watering of seedings can be done automatically by leveraging the development and advancement of technology, one of which is by utilizing a microcontroller that can be programmed to do watering according to the preferred time.
Gagassage Nanaluih De Side +5 more
doaj +1 more source
THE AMARANTH SEEDS AS A SOURCE OF NUTRIENTS AND BIOACTIVE SUBSTANCES IN HUMAN DIET
Barbara Skwaryło-Bednarz +5 more
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Effect of Fenugreek (Trigonella foenum-graecum L.) Seed Extracts on the Structure of Myofibrillar Protein Oxidation in Duck Meat [PDF]
Mingyue Chen +6 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Experimental Evidence for Seed Metabolic Allometry in Barrel Medic (Medicago truncatula Gaertn.) [PDF]
Jean‐Baptiste Domergue +6 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Variability in seed germination and seedling growth at the intra- and inter-provenance levels of Nothofagus glauca (Lophozonia glauca), an endemic species of Central Chile [PDF]
Rómulo Santelices Moya +5 more
openalex +1 more source
Improving the Sowing Properties of Safflower Dye Seeds Using a Vibrating Seed Cleaning Machine [PDF]
Oleksiy Kozachenko +5 more
openalex +1 more source

