Results 91 to 100 of about 1,884,327 (363)

Estimating Underlying Energy Demand Trends using UK Annual Data [PDF]

open access: yes
Employing the Structural Time Series Model (STSM) approach suggested by Harvey (1989, 1997), and based on annual data for the UK from 1967-2002, this paper reiterates the importance of using a stochastic rather than a linear deterministic trend ...
Guy Judge   +2 more
core  

Sowing Organic Seeds [PDF]

open access: yes, 2012
There is a growing realisation that only the adoption of ecological and sustainable farming practices can reverse the declining trend in farm productivity in the state of West Bengal, India. The paper is on how a small holding (3.8 acres) family farm in
Roy, Sabyasachi
core  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

What Bacteria Are Present in the Endosphere of Lettuce Seeds and Why?

open access: yesSeeds
Increasing demand for high-quality food is driving the development of biologized farming methods, which involve the use of microorganisms, including endophytes, to stimulate plant growth.
Polina Kuryntseva   +6 more
doaj   +1 more source

Food Superstores, Food Deserts and Traffic Generation in the UK: A Semi-Parametric Regression Approach [PDF]

open access: yes
This study contributes another route towards explaining and tackling ‘food desert’ effects. It features the estimation of a (semi-parametric) trip attraction model for food superstores in the UK using a composite dataset.
Alan Collins   +3 more
core  

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Optimal sliding scale regulation: An application to regional electricity distribution in England and Wales [PDF]

open access: yes
This paper examines optimal price (i.e. ‘sliding scale’) regulation of a monopoly when productivity and managerial effort are not observed. We show how to operationalise this model of incentive regulation and use actual data from electricity distribution
David Hawdon   +3 more
core  

An evaluation of osmotic pre-sowing seed treatments as a potential method for improving the germination performance of Pinus radiata D. Don seeds : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Seed Technology at Massey University [PDF]

open access: yes, 1992
This study was conducted lo characterise optimum conditions for osmotic pre-sowing treatment as an effective means of improving the germination and/or emergence performance of Pinus radiata from different seed grades.
Kusmintardjo
core  

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

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