Results 71 to 80 of about 644,839 (318)

Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds [PDF]

, 2013
This work was supported by a Wellcome Trust award to TMG.Mucopolysaccharidosis (MPS) I is a lysosomal storage disease caused by a deficiency of α-L-iduronidase (IDUA) (EC 3.2.1.76); enzyme replacement therapy is the conventional treatment for this ...
Brooks, Doug, Gloster, Tracey M., Vocadlo, D.J., Brooks, D., Kolarich, Daniel, Kermode, Allison R, Kermode, Allison R., Haselhorst, T., Qian, Y., Gloster, Tracey M, Qian, Yi, Gloster, Tracey, Kolarich, D., Haselhorst, Thomas, Packer, N.H., Pierce, Owen, He, X., von Itzstein, Mark, Gloster, T.M., Packer, Nicolle H., He, Xu, Pierce, O., Packer, Nicolle H, Vocadlo, David J, von Itzstein, M., Kermode, A.R., Vocadlo, David J.   +26 more
core   +1 more source

Seeds-Abs-GNRs complexes retain seeding ability and can be integrated into fibrillar networks.

, 2022
a) Aggregation kinetics assessed by ThT fluorescence of 10 μM Aβ40 in PBS (pH 7.4, 37°C) in absence (black) or presence of seeds at varying concentrations; 0.1 μM (orange), 0.5 μM (light blue), and 1 μM (yellow).
Jillian Madine (1869376), Mahmoud G. Soliman (3601703), Jack Sharkey (2836094), Raphaël Lévy (2650135), Hannah A. Davies (6851888)   +4 more
core   +1 more source

Grain yield and kernel crude protein content increases of maize hybrids with late nitrogen side-dressing

Scientia Agricola, 2005
Physiological changes incorporated into current maize hybrids suggest the occurrence of modifications in the nitrogen uptake dynamics, improving plant ability to uptake N during grain filling.
Paulo Regis Ferreira da Silva, Mércio Luiz Strieder, Rúbia Patrícia da Silva Coser, Lisandro Rambo, Luís Sangoi, Gilber Argenta, Everton Leonardo Forsthofer, Adriano Alves da Silva   +7 more
doaj  

Drought Stress Mitigation in Wheat Seedlings via Green-Synthesized Silver Nanoparticle Priming

Seeds
Drought is a major abiotic stress that compromises seed germination, seedling establishment, and subsequent crop productivity, thereby threatening agricultural sustainability and food security.
Saubhagya Subhadarsini Sahoo, Dwipak Prasad Sahu, Rajendra Kumar Behera   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Germination Potential of Six Native Plant Species for Phytoremediation of Hydrocarbon Contaminated Peat Soils

Seeds
Research on the remediation of hydrocarbon contaminated peatlands is limited; in particular, hydrocarbon effects on seed germination is critical for effective reclamation.
Mahdiyeh Safaripour-Chafi, Amalesh Dhar, Sarah R. Wilkinson, M. Anne Naeth   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Prevalence of Seed-Borne Fungi on Soybean (Glycine max L. Merr.) Seeds Stored Under Medium-Term Cold Room Facilities: Implications for Genebanks

Seeds
This study examined the prevalence of seed-borne fungi in polyethylene plastic-packaged soybean seeds stored in a genebank and identified factors influencing their incidence.
Abdul J Shango, Sognigbé N’Danikou, Shebati Ramadhani, Saphina Sumaye, Jonas Nickas, Michael L Daud   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Determination of Soybean Oil, Protein and Amino Acid Residues in Soybean Seeds by High Resolution Nuclear Magnetic Resonance (NMRS) and Near Infrared (NIRS)

, 2012
A detailed account is presented of our high resolution nuclear magnetic resonance (HR-NMR) and near infrared (NIR) calibration models, methodologies and validation procedures, together with a large number of composition analyses for soybean seeds.
I. Baianu, Tiefeng You, P Lozano, Randall Nelson, Doina Costescu, I. C. Baianu, Randall L. Nelson, Tiefeng You, P R. Lozano, Valentin Prisecaru   +9 more
core   +1 more source