Results 51 to 60 of about 374,965 (268)

In Vitro Germination of the Mediterranean Xerophytes Thymelaea hirsuta and Thymelaea tartonraira ssp. tartonraira as Affected by Scarification, Temperature, Photoperiod and Storage

Seeds
With the aim of developing an efficient propagation method for the exploitation of Thymelaea hirsuta and T. artonraira ssp. tartonraira in the xeriscaping and pharmaceutical industry, the effects of the following were examined on the in vitro germination
Aikaterini N. Martini, Maria Papafotiou
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

UVB Stress Induced Changes in Germination and Carbohydrate Mobilization in Chenopodium Quinoa Willd. Seeds

Seeds
Chenopodium quinoa Willd. (quinoa) is a very promising crop due to its nutraceutical properties and strong tolerance to extreme conditions, including high UVB. However, the physiological mechanisms underlying its adaptation to high UVB are still unclear,
Marco Carli, Lorenzo Guglielminetti, Thais Huarancca Reyes   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Osmopriming Increases Seed Germination of Amaranthus cruentus (L.)

Seeds
Amaranth is considered a gluten-free, protein-rich pseudocereal. However, seed dormancy affects the germination rate and production. The aim of this study was to investigate the effects of osmopriming, hydropriming, priming with Algal and chia-seed ...
Arnaud Busquère, Dominique Lefebvre, Patrice Galaup, Lucas Tricoulet, Charline Musset, Eric Lacroux, Othmane Merah   +6 more
doaj   +1 more source

IMPROVEMENT OF QUALITY OF SEEDING OF SEEDS OF SMALL SEED CROPS

VESTNIK RIAZANSKOGO GOSUDARSTVENNOGO AGROTEHNOLOGICHESKOGO UNIVERSITETA IM P A KOSTYCHEVA, 2020
Мелкосеменные культуры, такие как люцерна, клевер, рапс являются прекрасными кормовыми культурами и предшественниками для сельскохозяйственного производства. Нельзя забывать и о том, что из семян некоторых мелкосеменных культур производят альтернативные виды топлива, что весьма актуально при снижении мировых запасов углеводородов.
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Morpho-anatomical Study of 100 Tomato Lines

International Journal of Bio-Resource and Stress Management, 2014
A study has been undertaken of 100 genotypes of tomato grown in polyhouse during summer (April-May 2012) for general morphological and anatomical characters of leaves of one hundred tomato genotypes and its possible relation with drought and heat stress
Ratikanta Maiti, D. Rajkumar, Jagan, P. Vidyasagar   +3 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source