Results 121 to 130 of about 1,559,015 (310)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Innovative Approaches for Engineering the Seed Microbiome to Enhance Crop Performance

Seeds
Seed science is the comprehensive study of seeds. It encompasses their biology, production, technology, genetics, physiology, ecology, and applications in agriculture and conservation.
Piao Yang, Ling Lu, Abraham Condrich, Gavin A. Muni, Sean Scranton, Shixiang Xu, Ye Xia, Shuai Huang   +7 more
doaj   +1 more source

An evaluation of osmotic pre-sowing seed treatments as a potential method for improving the germination performance of Pinus radiata D. Don seeds : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Seed Technology at Massey University [PDF]

, 1992
This study was conducted lo characterise optimum conditions for osmotic pre-sowing treatment as an effective means of improving the germination and/or emergence performance of Pinus radiata from different seed grades.
Kusmintardjo
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Potential Use of Herbicide Seed Safener and Pre-Emergent Residual Herbicides When Establishing Tropical Perennial Grasses—A Preliminary Study

Seeds
Annual grass weeds can provide significant competition to an establishing sown tropical perennial grass pasture. At least two years of grass weed control prior to sowing is required to reduce the weed seed bank.
Suzanne P. Boschma, Hugh W. McDouall, Jonathan W. McLachlan   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Development of a Monitoring Plan for the Accidental Dispersal of Genetically Modified Oilseed Rape in Italy

Seeds
This paper presents a pilot project conducted by ISPRA and ARPA Campania to develop a monitoring protocol to detect the presence of genetically modified (GM) oilseed rape (Brassica napus) plants resulting from accidental seed dispersal during ...
Valentina Rastelli, Valeria Giovannelli, Giovanni Staiano, Pietro Massimiliano Bianco, Alfonso Sergio, Matteo Lener   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Quantification of Glucosinolates in Seeds by Solid-State ¹³C-Nuclear Magnetic Resonance (NMR)

Seeds
Solid-state 13C NMR spectroscopy using cross-polarization magic-angle spinning is a highly valuable technique for the semi-quantitative analysis of complex solid matrices.
Stefania Mazzini, Marco Zuccolo, Angela Bassoli, Claudio Gardana, Gigliola Borgonovo   +4 more
doaj   +1 more source

Modelling and Forecasting Turkish Residential Electricity Demand [PDF]

This research investigates the relationship between Turkish residential electricity consumption, household total final consumption expenditure and residential electricity prices by applying the structural time series model to annual data over the period ...
Lester C Hunt, Zafer Dilaver
core