Results 141 to 150 of about 2,889,259 (354)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

The socio economic drivers of rural electrification in Sub-Saharan Africa [PDF]

open access: yes
A significant proportion of the population in sub-Saharan Africa live in the rural areas, with the majority living on less than US$1 per day. Access to electricity is considered an essential element in the sustainable development of rural areas and an ...
Oona Nanka-Bruce
core  

The effects of calcium–silicate–hydrate (C–S–H) seeds on reference microorganisms [PDF]

open access: hybrid, 2020
Adrian Augustyniak   +6 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Efficiency and Performance in the Gas Industry [PDF]

open access: yes
Efficiency Performance Gas ...
David Hawdon
core  

Bright spots : seeds of a good Anthropocene

open access: yes, 2016
E. Bennett   +21 more
semanticscholar   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Turkish Aggregate Electricity Demand: An Outlook to 2020 [PDF]

open access: yes
This paper investigates the relationship between Turkish aggregate electricity consumption, GDP and electricity prices in order to forecast future Turkish aggregate electricity demand.
Lester C Hunt, Zafer Dilaver
core  

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