Results 31 to 40 of about 2,805,876 (348)

Vector seeds: An extension to spaced seeds

open access: yesJournal of Computer and System Sciences, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Daniel G. Brown   +2 more
openaire   +2 more sources

From the first stars to the first black holes [PDF]

open access: yes, 2016
The growth of the first super massive black holes (SMBHs) at z > 6 is still a major challenge for theoretical models. If it starts from black hole (BH) remnants of Population III stars (light seeds with mass ~ 100 Msun) it requires super-Eddington ...
Omukai, Kazuyuki   +3 more
core   +4 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Seed

open access: yesCarnivorous Plant Newsletter, 1975
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Germination responses in Callitriche truncata Gussone [PDF]

open access: yes, 2013
This study investigated the germination responses of seeds of Callitriche truncata, an obligate hydrophyte that colonises temporary ponds in the Mediterranean, when subjected to different depths of burial and to varying patterns of initial flooding, and ...
Camilleri, Jilly, Lanfranco, Sandro
core   +1 more source

Seeding the Garden

open access: yesEDIS, 2021
Growing your own Florida vegetable garden can be a rewarding experience with a little planning. This 5-page publication of the UF/IFAS Horticultural Sciences Department presents an overview of proper seed selection and planting. It also provides best management practices, as well as relevant terms and methods, for seeding vegetables in home and ...
James M. Stephens   +3 more
openaire   +5 more sources

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