Results 101 to 110 of about 2,141,304 (303)

Neural Models of Seeing and Thinking [PDF]

open access: yes, 2002
Air Force Office of Scientific Research (F49620-01-1-0397); Office of Naval Research (N00014-01-1 ...
Grossberg, Stephen
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Seeing Albertine Seeing: Barbey and Proust Through Balzac

open access: yesStudies in 20th & 21st Century Literature, 1990
The three texts, Balzac's La Fille aux yeux d'or , Barbey d'Aurevilly's Le Rideau cramoisi , and Proust's La Prisonnière , share two structuring themes: the problematic eyes of a woman who desires, and the need to see the woman in order to learn her ...
Dorothy Kelly
doaj   +1 more source

Photometric transit search for planets around cool stars from the Western Italian Alps: a site characterization study

open access: yes, 2010
We present the results of a site characterization study carried out at the Astronomical Observatory of the Autonomous Region of the Aosta Valley (OAVdA), in the Western Italian Alps, aimed at establishing its potential to host a photometric transit ...
Bernagozzi, A.   +7 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Seeing Through the Invisible Pink Unicorn [PDF]

open access: yes, 2010
This paper explores the quasi-religious aspects of the Invisible Pink Unicorn (IPU), an internet based spoof of religion. IPU message boards situate a moral orientation in an ongoing interactional process that sacralizes parody and an idealized form of ...
Abel, Andrew Stuart, Schaefer, Andrew P.
core   +1 more source

What is limiting near-infrared astrometry in the Galactic Center?

open access: yes, 2009
We systematically investigate the error sources for high-precision astrometry from adaptive optics based near-infrared imaging data. We focus on the application in the crowded stellar field in the Galactic Center. We show that at the level of
Alexander   +54 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy