Results 121 to 130 of about 418,245 (352)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Seeing fans: representations of fandom in media and popular culture

open access: yes, 2016
Split into four sections, Seeing Fans analyzes the representations of fans in the mass media through a diverse range of perspectives. This collection opens with a preface by noted actor and fan Orlando Jones (Sleepy Hollow), whose recent work on fandom ...

core  

Seeing Sound Dataset v1.0.1

open access: yes, 2017
<p>This is dataset contains the synthesized soundscapes and crowdsourced audio annotations that accompany the paper,</p> <blockquote> <p>M. Cartwright, A. Seals, J. Salamon, A. Williams, S. Mikloska, D. MacConnell, E.
Juan Pablo Bello   +17 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Seeing in VR, without Seeing-In

open access: yesEstetika
In The Aesthetics of Virtual Reality (2022), Grant Tavinor claims that VR is a technologically fancy kind of picturing and, more specifically, that VR headsets elicit proper seeing-in experiences.
Luca Marchetti
doaj   +1 more source

View of Washington Valley From The Grounds of the Seeing Eye

open access: yes, 2008
This is the view from the 62 acre campus of the Seeing Eye located in Washington Valley Morris Township.
Beards, Daniel E.
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Seeing the changing seasons

open access: yes, 2012
Educação Superior::Ciências Exatas e da Terra::GeoCiênciasEnsino Médio::GeografiaWintry weather brings cold temperatures and brown landscapes. This change in vegetation can be measured by satellites.
National Oceanic and Atmospheric Administration
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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