Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Practical Understandings: Teachers\u27 Beliefs And Practices In Pronunciation Teaching
, 2008 Recent discussion regarding pronunciation teaching and the global expansion of English use have encouraged formal English education in the EFL/expanding circle countries.The present study involved three native English speaking teachers (NEST) and three ...
Chiu, Hsing-Hui Winnie
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Teaching linguistic mimicry to improve second language pronunciation. [PDF]
, 2003 This thesis tests the hypothesis that a whole language approach to ESL (English As A Second Language) pronunciation with emphasis on suprasegementals through the use of linguistic mimicry is more effective than a focus on segmentals in improving native ...
Yates, Karen
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
La importancia de la competencia oral en la didáctica comunicativa de lenguas [PDF]
, 2021 Aquest volum 12 de la revista Phonica és un monogràfic de cinc articles al voltant de la didàctica de la competència oral i, especialment, de la pronunciació, entesa com l'ensenyament no només dels fenòmens segmentals sinó també dels suprasegmentls.This ...
Usó Viciedo, Lídia
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Teachers' and Learners' Beliefs About Pronunciation Instruction in Tertiary English as a Foreign Language Education. [PDF]
Front Psychol, 2021 Nguyen LT, Hung BP, Duong UTT, Le TT.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Condicions prosòdiques i minimitat en el tipus reduplicatiu 'puput'
, 2021 El propòsit d'aquest treball és descriure el procés morfològic de reduplicació parcial que ha format una sèrie de mots del català, agrupats sota el que anomenem tipus puput.
Cabré i Monné, Teresa
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Restriccions fonològiques i morfològiques en les combinacions de pronoms febles del valencià [PDF]
, 2022 És ben sabut que la combinació de pronoms febles és un dels terrenys que presenta més variació dialectal en català. El present treball pretén contribuir a l’estudi d’aquest camp a partir de l’anàlisi de dades de varietats del valencià que han estat poc ...
Jiménez, Jesús, Lloret, Maria-Rosa
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