Results 71 to 80 of about 500 (217)

A Comparative Analysis of Segmental and Suprasegmental Features of the Received Pronunciation (RP) and General American (GAM) [PDF]

, 2018
This is a comparative analysis of the Received Pronunciation (RP) and General American (GAM). The researcher adopted a theoretical approach. Two dialects: the RP and CAM are adequately and specifically considered.
OKEUGO, OLUCHI CHRIS, Ejike E., NWABUEZE,, Mercy, OKOYE,   +2 more
core  

Trends in Phonetics and Phonology

, 2015
This volume was inspired by the 9th edition of the Phonetik and Phonologie conference, held in Zürich in October 2013. It includes state of the art research on phonetics and phonology in various languages and from interdisciplinary contributors.

core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Minimizing transfer : including Spanish phonetics and phonology in curricula for beginner and intermediate university students of Spanish.

, 2017
This thesis explores the ways in which certain types of linguistic transfer, specifically phonetic and phonological, impact the second language acquisition process of university students whose target language is Spanish.
Lyles, Dustin R., 1992-
core   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Concordance of various chromosomal errors among different parts of the embryo and the value of re-biopsy in embryos with segmental aneuploidies. [PDF]

Mol Hum Reprod, 2020
Navratil R, Horak J, Hornak M, Kubicek D, Balcova M, Tauwinklova G, Travnik P, Vesela K.   +7 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Optimized NGS Approach for Detection of Aneuploidies and Mosaicism in PGT-A and Imbalances in PGT-SR. [PDF]

Genes (Basel), 2020
García-Pascual CM, Navarro-Sánchez L, Navarro R, Martínez L, Jiménez J, Rodrigo L, Simón C, Rubio C.   +7 more
europepmc   +1 more source

Comparison of euploid blastocyst expansion with subgroups of single chromosome, multiple chromosome, and segmental aneuploids using an AI platform from donor egg embryos. [PDF]

J Assist Reprod Genet, 2023
Hori K, Hori K, Kosasa T, Walker B, Ohta A, Ahn HJ, Huang TTF.   +6 more
europepmc   +1 more source