Results 61 to 70 of about 500 (217)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

The Inflecting Stems of Proto-Korean

open access: yes, 1986
The proto forms of Korean verbs are reconstructed through the method of internal reconstruction, supplemented by comparative evidence from the modern dialects.
Ramsey, S. Robert
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Crash modules to help Persians speak more intelligible and comprehensible English, emphasizing either production or perception of either sounds or melodies [PDF]

open access: yes
Yenkimaleki and van Heuven (2021) studied the effects of teaching either segmental or suprasegmental (prosodic) aspects of English, in combination with either perception or production-focused practice (four combinations in all) on the speech ...
Heuven, V.J.J.P. van, Yenkimaleki, M.
core   +1 more source

English Segmental Pedagogy, Homophonic Realisation And Communicative Competence In L2

open access: yesThe Journal of Studies in Language, Culture and Society
The study investigates and compares the performance of two groups of final year English major undergraduates of a Nigerian University in the production and perception of homophones.
Julianah Ajoke Akindele   +1 more
doaj  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

An exploratory study of foreign accent and phonological awareness in Korean learners of English [PDF]

open access: yes, 2019
Communication in a second or multiple languages has become essential in the globalized world. However, acquiring a second language (L2) after a critical period is universally acknowledged to be challenging (Lenneberg, 1967).
Park, Mi Sun
core   +1 more source

The Influence of Minor Aortic Branches in Patient-Specific Flow Simulations of Type-B Aortic Dissection. [PDF]

open access: yesAnn Biomed Eng, 2023
Stokes C   +6 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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