Results 101 to 110 of about 1,383,033 (265)

Joint Brain Tumor Segmentation from Multi-magnetic Resonance Sequences through a Deep Convolutional Neural Network

open access: yesJournal of Medical Signals and Sensors
Background: Brain tumor segmentation is highly contributive in diagnosing and treatment planning. Manual brain tumor delineation is a time-consuming and tedious task and varies depending on the radiologist’s skill.
Farzaneh Dehghani   +2 more
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

An Ore Image Segmentation Method Based on RDU-Net Model [PDF]

open access: gold, 2020
Dong Xiao   +4 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

High throughput assessment of blueberry fruit internal bruising using deep learning models

open access: yesFrontiers in Plant Science
The rising costs and labor shortages have sparked interest in machine harvesting of fresh-market blueberries. A major drawback of machine harvesting is the occurrence of internal bruising, as the fruit undergoes multiple mechanical impacts during this ...
Chenjiao Tan   +5 more
doaj   +1 more source

RailNet: A Segmentation Network for Railroad Detection [PDF]

open access: gold, 2019
Yin Wang, Lide Wang, Yu Hen Hu, Ji Qiu
openalex   +1 more source

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