Results 81 to 90 of about 1,383,033 (265)

Deep Learning-Based Fully Automatic Segmentation of the Paranasal Sinuses in Chronic Rhinosinusitis Patients Using Computed Tomographic Images

IEEE Access
Chronic rhinosinusitis with nasal polyps (CRSwNP), as one of the most common chronic nasal inflammations, has been a major research focus in the field of rhinology due to its complex and varied pathophysiological features and suboptimal clinical ...
Yuhang Wang, Xiaolei Zhang, Weidong Du, Na Dai, Yi Lyv, Keying Wu, Yiyang Tian, Yuxin Jie, Yu Lin, Weipiao Kang   +9 more
doaj   +1 more source

Analyzing the Quality and Challenges of Uncertainty Estimations for Brain Tumor Segmentation [PDF]

, 2020
Alain Jungo, Fabian Balsiger, Mauricio Reyes   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Uncertainty-Aware Semi-Supervised Method for Pectoral Muscle Segmentation

Bioengineering
The consistency regularization method is a widely used semi-supervised method that uses regularization terms constructed from unlabeled data to improve model performance.
Yutao Tang, Yongze Guo, Huayu Wang, Ting Song, Yao Lu   +4 more
doaj   +1 more source

Automated tumor segmentation and brain tissue extraction from multiparametric MRI of pediatric brain tumors: A multi-institutional study [PDF]

, 2023
Anahita Fathi Kazerooni, Sherjeel Arif, Rachel Madhogarhia, Nastaran Khalili, Debanjan Haldar, Sina Bagheri, Ariana Familiar, Hannah Anderson, Shuvanjan Haldar, Wenxin Tu, Meen Chul Kim, Karthik Viswanathan, Sabine Müller, Michael Prados, Cassie Kline, Lorenna Vidal, Mariam Aboian, Phillip B. Storm, Adam Resnick, Jeffrey B. Ware, Arastoo Vossough, Christos Davatzikos, Ali Nabavizadeh   +22 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Body position influence on cerebrospinal fluid volume redistribution inside the cranial and spinal CSF compartments

Frontiers in Human Neuroscience
IntroductionIt is generally accepted that during body position changes from horizontal to vertical there is a short-lasting shift of a certain CSF volume from the cranium into the hydrostatically lower parts of the spinal space, which leads to transitory
I. Strbačko, M. Radoš, I. Jurjević, D. Orešković, M. Klarica, M. Klarica   +5 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

A segmentation method for LiDAR point clouds of aerial slender targets

Frontiers in Physics
LiDAR (Light Detection and Ranging) is an essential device for capturing the depth information of objects. Unmanned aerial vehicles (UAV) can sense the surrounding environment through LiDAR and image sensors to make autonomous flight decisions.
Birong Huang, Zilong Wang, Jianhua Chen, Bingyang Zhou, Hao Ma   +4 more
doaj   +1 more source

SSMD-UNet: semi-supervised multi-task decoders network for diabetic retinopathy segmentation [PDF]

, 2023
Zahid Ullah, Muhammad Usman, Siddique Latif, Asifullah Khan, Jeonghwan Gwak   +4 more
openalex   +1 more source