Results 61 to 70 of about 23,265,687 (345)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Bayesian Spatial Binary Regression for Label Fusion in Structural Neuroimaging

, 2019
Many analyses of neuroimaging data involve studying one or more regions of interest (ROIs) in a brain image. In order to do so, each ROI must first be identified.
Brown, D. Andrew, Linn, Kristin A., McMahan, Christopher S., Shinohara, Russell T.   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Model and Optimization of the Tether for a Segmented Space Elevator

Aerospace, 2022
In order to improve the shortcomings of the traditional constant section and gradual section space elevator system, combined with the advantages of constant section and gradual section space elevator system, a model of segmented space elevator system is ...
Shihao Luo, Naigang Cui, Xiaowei Wang, Youhua Fan, Run Shi   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Creation of virtual worlds from 3D models retrieved from content aware networks based on sketch and image queries [PDF]

, 2011
The recent emergence of user generated content requires new content creation tools that will be both easy to learn and easy to use. These new tools should enable the user to construct new high-quality content with minimum effort; it is essential to allow
Daras, Petros, Makris, Lambros, McGuinness, Kevin, O'Connor, Noel E., Semertzidis, Theodoros, Strintzis, Michael G.   +5 more
core  

The use of segmented regression for evaluation of an interrupted time series study involving complex intervention: the CaPSAI project experience

Health Services & Outcomes Research Methodology, 2020
An interrupted time series with a parallel control group (ITS-CG) design is a powerful quasi-experimental design commonly used to evaluate the effectiveness of an intervention, on accelerating uptake of useful public health products, and can be used in ...
N. Habib, P. Steyn, Victoria Boydell, J. Cordero, My Huong Nguyen, S. Thwin, Dela Nai, D. Shamba, J. Kiarie, Ndema Petrus S. Victoria Joanna Paula My Huong Soe Soe D Habib Steyn Boydell Cordero Nguyen Thwin Nai Shamb, N. Habib, P. Steyn, Victoria Boydell, J. Cordero, My Huong Nguyen, S. Thwin, Dela Nai, D. Shamba, J. Kiarie   +18 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Experimental Evaluation for the Microvibration Performance of a Segmented PC Method Based High Technology Industrial Facility Using 1/2 Scale Test Models

Shock and Vibration, 2017
The precast concrete (PC) method used in the construction process of high technology industrial facilities is limited when applied to those with greater span lengths, due to the transport length restriction (maximum length of 15~16 m in Korea) set by ...
Sijun Kim, Se Woon Choi
doaj   +1 more source

Super Multi-Armed and Segmented Spiral Pattern in a Reaction-Diffusion Model

IEEE Access, 2019
The super multi-armed and segmented (SMAS) spiral pattern has been observed in nature, such as sunflower inflorescence, spiral aloe, pine cone, ball cactus and Roman broccoli, which is characterized by several segmented spiral arms sharing the same ...
Jian Gao, Changgui Gu
doaj   +1 more source