Results 31 to 40 of about 1,063,527 (322)

Evidence of substrate control of Cdk phosphorylation during the budding yeast cell cycle

Cell Reports
Summary: A series of sequential events orchestrates cell growth and division, set in motion by cyclin-dependent kinases (Cdks). In the “qualitative model” for Cdk control, order is achieved by cell cycle stage-specific cyclins.
Luca Takacs, Lina Gerontogianni, Kimberly Quililan, Helen Flynn, Frank Uhlmann   +4 more
doaj   +1 more source

Lessons from the Discovery of Mitochondrial Fragmentation (Fission): A Review and Update

Cells, 2019
Thirty-five years ago, we described fragmentation of the mitochondrial population in a living cell into small vesicles (mitochondrial fission). Subsequently, this phenomenon has become an object of general interest due to its involvement in the process ...
Dmitry B. Zorov, Ivan A. Vorobjev, Vasily A. Popkov, Valentina A. Babenko, Ljubava D. Zorova, Irina B. Pevzner, Denis N. Silachev, Savva D. Zorov, Nadezda V. Andrianova, Egor Y. Plotnikov   +9 more
doaj   +1 more source

Instant Drinks with Amaranth Flour: Simulation of Mechatronic Systems of Production [PDF]

Техника и технология пищевых производств, 2020
Introduction. The world market of instant drinks is a highly competitive environment. New mechatronic production systems can help food companies maintain their competitiveness: they determine process modes, analyze them, and choose the optimal ...
Popov Anatoly M. , Plotnikov Konstantin B. , Ivanov Pavel P., Donya Denis V. , Pachkin Sergei G. , Plotnikova Irina O.   +5 more
doaj   +1 more source

Quantifying the Energetics and Length Scales of Carbon Segregation to Fe Symmetric Tilt Grain Boundaries Using Atomistic Simulations

, 2013
Segregation of impurities to grain boundaries plays an important role in both the stability and macroscopic behavior of polycrystalline materials. The research objective in this work is to better characterize the energetics and length scales involved ...
Balluffi R W, Briant C L, Chen Q Z, Cowan J R, Foiles S M, K N Solanki, Kart H H, Li J, Liu X, M A Tschopp, N R Rhodes, Pugh S F, Sutton A P, Taheri M L, Takahashi H, Takahashi J, Yuasa M, Zhang L   +17 more
core   +1 more source

Luminosity- and morphology-dependent clustering of galaxies [PDF]

, 2000
How does the clustering of galaxies depend on their inner properties like morphological type and luminosity? We address this question in the mathematical framework of marked point processes and clarify the notion of luminosity and morphological ...
Alimi J.-M., Andreon S., Binggeli B., Borner G., Caon N., Capobianco R., Cappi A., Coles P., Dalton G., Dominguez-Tenreiro R., Gardini A., Hermit S., Kates R., Kauffmann G., Kerscher M., Kerscher M., Mann R. G., Mecke K. R., Stoyan D., van Lieshout M. N. M., van Lieshout M. N. M., Walder O., Weiss A. G.   +22 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Efeito da autofecundação em cultivares de abacaxi Effects of self pollination in pineapple cultivars

Revista Brasileira de Fruticultura, 2003
O elevado nível de heterozigose dos parentais utilizados em hibridações é a principal causa da baixa eficiência dos programas de melhoramento genético do abacaxizeiro em gerar novas cultivares.
José Renato Santos Cabral, Antônio da Silva Souza, Aristoteles Pires de Matos, Ranulfo Corrêa Caldas   +3 more
doaj   +1 more source

Female participation increases and gender segregation. ESRI WP564, May 2017 [PDF]

, 2017
This article examines the impact of a large increase in female participation on occupational segregation. Increases in female participation may decrease occupational segregation if women enter male dominated sectors but may increase segregation if they ...
Keane, Claire, Russell, Helen, Smyth, Emer   +2 more
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source