Results 91 to 100 of about 370,164 (308)
LifeThis study evaluated the utility of the 2HELPS2B score in predicting seizures from routine electroencephalographs (rEEGs). In total, 670 rEEGs obtained in a medical intensive care unit (MICU) between October 2018 and March 2023 were analyzed.
Cheng-Lun Hsiao +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Short- and long-term seizure-free outcomes of dietary treatment in infants according to etiology
, 2019 PURPOSE: It is important to determine whether specific etiology is more effective to dietary treatment so that the diet can be started earlier for infants. We evaluated etiology-specific, seizure-free outcomes of dietary treatment in infants
김세희 +4 more
core +1 more source
Treatment registry in focal epilepsy (TRIP): Multicenter observational study in Lebanon [PDF]
, 2015 Purpose Treatment of newly diagnosed epilepsy with a single antiepileptic drug (AED) is the favored approach for seizure management. This observational study aimed to assess, under daily practice conditions, remission and retention rates with the first ...
Ezzeddine, Kamel +5 more
core +1 more source
NeuroSciSeizure clusters can be observed in patients with epilepsy as well as in individuals without a previous history of epilepsy. However, there are no data on whether seizure clusters differ between these two populations.
Silvio Basic +5 more
doaj +1 more source
Nasal pregabalin overdose and myclonus: a new way of misuse
Psychiatry and Clinical Psychopharmacology, 2019 Pregabalin reduces central neuronal excitability and has gamma-aminobutyric acid-mimetic features, which was demonstrated in rats. Pregabalin is indicated for the treatment of neuropathic pain, post-herpetic neuralgia, fibromyalgia and partial seizures ...
H. Mihrimah Ozturk, Gülin Morkavuk
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2018 The current paradigm for treatment of epilepsy begins with trials of antiepileptic drugs, followed by evaluation for resective brain surgery in drug-resistant patients.
Rao, V. R., Baud, Maxime Olivier
core +1 more source
Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department
Frontiers in NeurologyBackgroundStatus epilepticus (SE) is a medical emergency that requires immediate care and is associated with substantial mortality and morbidity. Current guidelines recommend benzodiazepines (BZDs), regardless of the type of SE, as an initial treatment ...
Raniah Ibrahim Aljadeed +7 more
doaj +1 more source
Anticonvulsant Effect of Hydroalcoholic Extract of Scrophularia Striata Boiss. on Pentylenetetrazol-Induced Seizure in Mice [PDF]
Journal of Kerman University of Medical Sciences, 2014 Background & Aims: Epilepsy is a central nervous system disorder that appears as sudden convulsions, and transient, repetitive and unpredictable movment, with sensory-motor and autonomic sources.
B Alimohammadi +3 more
doaj