Results 101 to 110 of about 338,240 (315)

Interactions of caffeine and nitric oxide on pentylenetetrazole-induced clonic and tonic seizures in mice [PDF]

Basic and Clinical Biochemistry and Nutrition
Background: Caffeine, a non-selective antagonist of adenosine receptors (ARs), may affect the anticonvulsant properties of adenosine through modulation of the nitric oxide (NO) pathway.Objectives: This study aimed to investigate the impact of caffeine ...
Hassan Jamali, Azhdar Heydari
doaj   +1 more source

Vagus nerve stimulation in 15 children with therapy resistant epilepsy; its impact on cognition, quality of life, behaviour and mood. [Elektronisk resurs]

, 2005
PURPOSE: Vagus nerve stimulation (VNS) is a neurophysiologic treatment for patients with refractory epilepsy. There is growing evidence of additional quality of life (QOL) benefits of VNS.
Rosén, Ingmar,, Lundgren, Johan,, Hallböök, Tove,, Strömblad, Lars-Göran,, Stjernqvist, Karin,, Blennow, Gösta,, Lund University.   +6 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Assessment of the Efficacy, Safety, and Challenges of Ketogenic Diet Therapy in Children with Epilepsy: The First Experience of a Single Center

Medicina
Background and Objectives: Ketogenic diet therapy (KDT) has been used as a non-pharmacological treatment for childhood refractory epilepsy. Its efficacy and safety have been described in numerous studies and reviews.
Jurgita Karandienė, Milda Endzinienė, Karolina Liaušienė, Giedrė Jurkevičienė   +3 more
doaj   +1 more source

Emergency Care Of Children With Febrile Seizure

, 2020
Febrile seizure is the most prevalent neurological event in the childhood population, which can affect 2-5% of children of 3 months and 5 years of age. Although it is a benign seizure with favorable outcome, it is indeed a frightening event to parents ...
Nguyen, Le Uyen Phuong
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Gun seizure law

, 2009
Title from Web page (OLR web site, viewed Aug. 19, 2009).; "August 13, 2009."; Updates OLR research report 2008-R-0280 on the state's gun seizure law.; Harvested from the web on 8/19 ...
Rose, Veronica.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Insight into the Role of Ferroptosis in Epilepsy

Journal of Integrative Neuroscience
Excessively high or synchronized neuronal activity in the brain is the underlying cause of epilepsy, a condition of the central nervous system. Epilepsy is caused mostly by an imbalance in the activity of inhibitory and excitatory neural networks ...
Limin Huang, Haiyan Liu, Songyan Liu
doaj   +1 more source

Treatment of epilepsy in multiple sclerosis

, 2018
Purpose: The prevalence of epilepsy is increased in multiple sclerosis (MS), but information on AED treatment and seizure outcome is scarce. We describe epilepsy characteristics including the use of AEDs and proportion of seizure-free patients at two ...
Burman, Joachim,, Dagiasi, Loanna,, Vall, Victor,, Kumlien, Eva,, Zelano, Johan,   +4 more
core   +1 more source