Results 101 to 110 of about 370,164 (308)
Of the many risk factors suggested for sudden unexpected death in epilepsy (SUDEP), higher frequency of seizures is a very consistent issue. Following this reasoning, it has been established that hemodialysis-associated seizure is a complication of ...
Rui A. Gomes +12 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Title from Web page (OLR web site, viewed Aug. 19, 2009).; "August 13, 2009."; Updates OLR research report 2008-R-0280 on the state's gun seizure law.; Harvested from the web on 8/19 ...
Rose, Veronica.
core +1 more source
Extracellular potassium concentration, [K+]o, plays a fundamental role in the physiological functions of the brain. Studies investigating changes in [K+]o have predominantly relied upon glass capillary electrodes with K+-sensitive solution gradients for ...
Ruben Machado +6 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The Temporal Relation Between Seizure Onset And Arousal-Awakening In Temporal Lobe Seizures
Purpose: Our main aim was to determine the time interval between the seizure onsets and arousal awakening related to these seizures in patients with temporal lobe epilepsy (TLE) and to discuss the role of lateralization on arousal-awakening mechanisms ...
Tezer, F. Irsel +4 more
core +1 more source
Surgery for temporal lobe epilepsy in Semarang,Indonesia: The first 56 patients with follow up longer than 12 months [PDF]
Until October 2005, surgery were performed for 76 intractable temporal lobe epilepsy patients. Among them, 56 patients had follow-up of 12-76 months. The patients consisted of 35 males and 21 females,age between 3-38 year-old.
Muttaqin, Zainal
core +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

