Results 121 to 130 of about 1,164,710 (315)

A Genetical Theory of Species Selection

Journal of Theoretical Biology, 1995
Species selection, differential rates of speciation or extinction resulting from species level characters, is often invoked as the main mechanism of macroevolution that is not simply an extension of microevolutionary processes. So long as we are careful in defining "species", the logic of species selection is sound.
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Genetic parameters for social effects on survival in cannibalistic layers: Combining survival analysis and a linear animal model

, 2010
Background Mortality due to cannibalism in laying hens is a difficult trait to improve genetically, because censoring is high (animals still alive at the end of the testing period) and it may depend on both the individual itself and the behaviour of its ...
Veerkamp Roel F, Veerkamp, Roel F., Ducrocq, V.P., Ducrocq, Vincent, Bijma, Piter, Bijma Piter, Ducro, B.J., Esther D Ellen, Ellen, Esther D., Bijma, P., Ellen Esther D, Ellen, E.D., Veerkamp, Roel F, Roel F Veerkamp, Ducro, Bart J., Veerkamp, R.F., Vincent Ducrocq, Ducro Bart J, Bart J Ducro, Ducrocq Vincent, Ducro, Bart J, Piter Bijma   +21 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Genetic Variation in Provenance-Progeny Trials of Cupre-ssus sempervirens in Türkiye

South-East European Forestry
In this study, the genetic and phenotypic relations among tree height, diameter at breast height and survival at 18 years of age were investigated in Mediterranean cypress (Cupressus sempervirens L. var.
Alper Ahmet Özbey, Mehmet Çalikoğlu, Rumi Sabuncu, Zeynep Gülçin Altun   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genome-Wide Footprints of Pig Domestication and Selection Revealed through Massive Parallel Sequencing of Pooled DNA

, 2011
Background Artificial selection has caused rapid evolution in domesticated species. The identification of selection footprints across domesticated genomes can contribute to uncover the genetic basis of phenotypic diversity.
Perez-Enciso, M., Schook, L.B., Nie, H., Crooijmans, R.P.M.A., Groenen, M.A.M., Ferretti, L., Amaral, A.J., Megens, H.J.W.C., Ramos-Onsins, S.E.   +8 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

GSE’s 50th anniversary: where do we go from now?

Genetics Selection Evolution, 2019
Genetic Selection Evolution’s Editorial Board
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source