Results 141 to 150 of about 1,093,370 (267)

Expression of Concern: Comprehensive framework for thyroid disorder diagnosis: Integrating advanced feature selection, genetic algorithms, and machine learning for enhanced accuracy and other performance matrices. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Comprehensive framework for thyroid disorder diagnosis: Integrating advanced feature selection, genetic algorithms, and machine learning for enhanced accuracy and other performance matrices. [PDF]

PLoS One
Kumar A, Dhanka S, Sharma A, Sharma A, Maini S, Fahlevi M, Rabby F, Aljuaid M, Bansal R.   +8 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Positive selection, genetic recombination, and intra-host evolution in novel equine coronavirus genomes and other members of the <i>Embecovirus</i> subgenus. [PDF]

Microbiol Spectr
Zehr JD, Kosakovsky Pond SL, Shank SD, McQueary H, Grenier JK, Whittaker GR, Stanhope MJ, Goodman LB.   +7 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Selection methods to optimize the gain and genetic diversity in Pinus caribaea var. caribaea

Crop Breeding and Applied Biotechnology
We estimated genetic parameters of two Pinus caribaea var. caribaea progeny tests based on growth traits aiming at the identification of the best selection strategy. This study was conducted in two progeny tests located in Selvíria (MS), Brazil.
Daniele Fernanda Zulian, Bruno Marchetti de Souza, Darlin Gonzalez, Jose Cambuim, Alexandre Marques da Silva, Patrícia Ferreira Alves, Maria Teresa Gomes Lopes, Mario Luiz Teixeira de Moraes, Ananda Virginia de Aguiar   +8 more
doaj  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Balancing gain and diversity: Optimal contribution selection for sustainable genetic improvement in sugarcane. [PDF]

Plant Genome
Vo Van-Zivkovic N, Hayes BJ, Aitken K, Dinglasan E, Morgan T, Yadav S.   +5 more
europepmc   +1 more source