Results 131 to 140 of about 529,543 (309)
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Evolutionary Consequences of Sex Linkage and Sex-Specific Selection. [PDF]
Males and females make equal genetic contributions to each generation, yet each sex is exposed to different, sometimes opposing forces of natural and sexual selection.
Connallon, Timothy M.
core
Shrub avoidance by an open-adapted ground squirrel in a shrub-encroached environment.
PLoS ONEHabitat loss and degradation are leading drivers of the widespread decline in wildlife populations, and understanding how wildlife perceive and navigate their environment is useful for predicting responses to future landscape changes.
Alexandra D Burnett, John L Koprowski
doaj +1 more source
Consequences of selection for egg weight on hatchability [PDF]
Genetics Selection Evolution, 1978 Flock DK, Mergl R, Pirchner F
openaire +4 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Habitat-Selecting Life History
FishesAdaptive life histories emerge through their environmentally dependent effects on fitness. Those effects are consequences of habitat quality and the density-dependent decisions that organisms make on habitat choice. Density dependence for ideal organisms
Douglas W. Morris, Per Lundberg
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Positive selection underlies Faster-Z evolution of gene expression in birds.
, 2015 The elevated rate of evolution for genes on sex chromosomes compared to autosomes (Fast-X or Fast-Z evolution) can result either from positive selection in the heterogametic sex, or from non-adaptive consequences of reduced relative effective population ...
Zimmer, F +4 more
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Selection in Insurance Markets: Theory and Empirics in Pictures [PDF]
We present a graphical framework for analyzing both theoretical and empirical work on selection in insurance markets. We begin by using this framework to review the “textbook” adverse selection environment and its implications for insurance allocation ...
Liran Einav, Amy Finkelstein
core