Results 51 to 60 of about 57,726,953 (253)
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad +9 more
wiley +1 more source
Sexual selection in a transparent worm : insights from fluorescent sperm [PDF]
Sexual selection is a potent source of selection underlying the evolution of sexual dimorphism, reproductive strategies and mating systems. Although sexual selection was initially thought to occur exclusively at the pre-copulatory stage (e.g., contests ...
Marie-Orleach, Lucas
core +1 more source
How frequency‐dependent selection affects population fitness, maladaptation and evolutionary rescue
Frequency‐dependent (FD) selection is a central process maintaining genetic variation and mediating evolution of population fitness. FD selection has attracted interest from researchers in a wide range of biological subdisciplines, including evolutionary
Erik I. Svensson, Tim Connallon
doaj +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Entropy and Selection: Life as an Adaptation for Universe Replication
Natural selection is the strongest known antientropic process in the universe when operating at the biological level and may also operate at the cosmological level.
Michael E. Price
doaj +1 more source
Seasonal variation in preference dictates space use in an invasive generalist. [PDF]
BACKGROUND:The spatiotemporal distribution of resources is a critical component of realized animal distributions. In agricultural landscapes, space use by generalist consumers is influenced by ephemeral resource availability that may produce behavioral ...
Kelsey E Paolini +4 more
doaj +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Other title: Title from HTML header (viewed Nov. 9, 2011): Judicial Selection Commission
Updated irregularly; Began in 2002?; Title from main search screen (publisher's Web site, viewed Nov. 9, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/1/14Official website of the Connecticut Judicial Selection Commission ...
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