Results 61 to 70 of about 529,543 (309)

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Models of cultural niche construction with selection and assortative mating

, 2012
This research was supported in part by National Institutes of Health grant GM28016 and a Biotechnology and Biological Sciences Research Council studentship to LF. The funders had no role in study design, data collection and analysis, decision to publish,
Fogarty, Laurel, Creanza Nicole, Marcus W. Feldman (143724), Laurel Fogarty (143721), Fogarty Laurel, Feldman Marcus W., Laurel Fogarty, Nicole Creanza (143720), Feldman, Marcus W., Creanza, Nicole, Marcus W Feldman, Nicole Creanza   +11 more
core   +1 more source

Molecular mechanisms of adaptive evolution revealed by global selection for glyphosate resistance [PDF]

, 2019
The human‐directed, global selection for glyphosate resistance in weeds has revealed a fascinating diversity of evolved resistance mechanisms, including herbicide sequestration in the vacuole, a rapid cell death response, nucleotide polymorphisms in the ...
Todd A. Gaines, Neve, P., Gaines, T. A., Eric L. Patterson, Patterson, E. L., Paul Neve   +5 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Amorous scorpionflies: causes and consequences of the long pairing prelude of Panorpa cognata

, 2002
Engqvist L, Sauer KP. Amorous scorpionflies: causes and consequences of the long pairing prelude of Panorpa cognata. Animal Behaviour. 2002;63(4):667-675.The scorpionfly Panorpa cognata has a prolonged premating period.
Sauer, Klaus Peter, Engqvist, Leif ; https://orcid.org/   +1 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Pathological and ecological host consequences of infection by an introduced fish parasite

, 2011
The infection consequences of the introduced cestode fish parasite Bothriocephalus acheilognathi were studied in a cohort of wild, young-of-the-year common carp Cyprinus carpio that lacked co-evolution with the parasite.
Pegg Josephine, Williams Chris F., Britton J. Robert, Pegg, Josie, J. Robert Britton, Britton, J.R., Chris F Williams, Josephine Pegg, J Robert Britton, Williams, C.F., Chris F. Williams   +10 more
core   +1 more source

Killing them softly:managing pathogen polymorphism and virulence in spatially variable environments [PDF]

, 2013
Understanding why pathogen populations are genetically variable is vital because genetic variation fuels evolution, which often hampers disease control efforts.
Vale, Pedro F; id_orcid, Vale, Pedro F.
core   +1 more source

How frequency‐dependent selection affects population fitness, maladaptation and evolutionary rescue

Evolutionary Applications, 2019
Frequency‐dependent (FD) selection is a central process maintaining genetic variation and mediating evolution of population fitness. FD selection has attracted interest from researchers in a wide range of biological subdisciplines, including evolutionary
Erik I. Svensson, Tim Connallon
doaj   +1 more source