Results 81 to 90 of about 1,311,332 (340)

Optimization of Combat Resource Allocation Based on Restricted Tournament Selection Social Genetic Algorithm

International Journal of Computational Intelligence Systems
To tackle the challenge of combat resource allocation problem (CRAP), especially under resource constraints, the dilemma between the efficiency of combat resource utilization and the efficiency of problem-solving.
Shandong Yuan, Yun Ren, Han Zhou, Yongjing Cheng, Kai Yan   +4 more
doaj   +1 more source

Evolutionary sequential genetic search technique-based cancer classification using fuzzy rough nearest neighbour classifier

Healthcare Technology Letters, 2018
Cancer is one of the deadly diseases of human life. The patient may likely to survive if the disease is diagnosed in its early stages. In this Letter, the authors propose a genetic search fuzzy rough (GSFR) feature selection algorithm, which is ...
Loganathan Meenachi, Srinivasan Ramakrishnan   +1 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Genetic Algorithm (GA) in Feature Selection for CRF Based Manipuri Multiword Expression (MWE) Identification

, 2011
This paper deals with the identification of Multiword Expressions (MWEs) in Manipuri, a highly agglutinative Indian Language. Manipuri is listed in the Eight Schedule of Indian Constitution.
Bandyopadhyay, Sivaji, Nongmeikapam, Kishorjit   +1 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Underwater target classification with optimized feature selection based on Genetic Algorithms [PDF]

, 2020
Rigel Procópio Fernandes, José Jr.
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Enhanced Feature Selection Using Genetic Algorithm for Machine-Learning-Based Phishing URL Detection

Applied Sciences
In recent years, the importance of computer security has increased due to the rapid advancement of digital technology, widespread Internet use, and increased sophistication of cyberattacks.
Emre Kocyigit, Mehmet Korkmaz, Ozgur Koray Sahingoz, Banu Diri   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Mobile transporter path planning [PDF]

The use of a genetic algorithm (GA) for solving the mobile transporter path planning problem is investigated. The mobile transporter is a traveling robotic vehicle proposed for the space station which must be able to reach any point of the structure ...
Baffes, Paul, Wang, Lui
core   +1 more source