Results 151 to 160 of about 3,585,940 (324)

Multiple Instance Hybrid Estimator for Learning Target Signatures

, 2017
Signature-based detectors for hyperspectral target detection rely on knowing the specific target signature in advance. However, target signature are often difficult or impossible to obtain.
Jiao, Changzhe, Zare, Alina
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Increasing stability and interpretability of gene expression signatures

, 2010
Motivation : Molecular signatures for diagnosis or prognosis estimated from large-scale gene expression data often lack robustness and stability, rendering their biological interpretation challenging.
Haury, Anne-Claire, Jacob, Laurent, Vert, Jean-Philippe   +2 more
core   +1 more source

Polarization selection rules for inter-Landau level transitions in epitaxial graphene revealed by infrared optical Hall effect

, 2013
We report on polarization selection rules of inter-Landau level transitions using reflection-type optical Hall effect measurements from 600 to 4000 cm-1 on epitaxial graphene grown by thermal decomposition of silicon carbide.
Darakchieva, V., Eddy Jr., C. R., Gaskill, D. K., Herzinger, C. M., Hofmann, T., Kühne, P., Myers-Ward, R. L., Schubert, M., Tedesco, J. D., Woollam, J. A., Yakimova, R.   +10 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Assessment of selective breeding effects and selection signatures in Qingyuan partridge chicken and its strains

Poultry Science
: Qingyuan partridge chicken (QYM) is a highly regarded native breed in China, highly esteemed for its exceptional breeding characteristics. However, the investigation into the selection signatures and its strains remains largely unexplored.
Shaofen Kong, Bolin Cai, Xiaojing Li, Zhen Zhou, Xiang Fang, Xin Yang, Danfeng Cai, Xuehui Luo, Suyin Guo, Qinghua Nie   +9 more
doaj   +1 more source

Many-body excitations in tunneling current spectra of a few-electron quantum dot

, 2007
Inherent asymmetry in the tunneling barriers of few-electron quantum dots induces intrinsically different tunneling currents for forward and reverse source-drain biases in the non-linear transport regime.
D. G. Austing, D. V. Melnikov, J. J. Palacios, J.-P. Leburton, L. P. Kouwenhoven, M. Wagner, S. Tarucha, T. Fujisawa   +7 more
core   +1 more source

A genome-wide scan for diversifying selection signatures in selected horse breeds

PLoS ONE, 2019
The genetic differentiation of the current horse population was evolutionarily created by natural or artificial selection which shaped the genomes of individual breeds in several unique ways. The availability of high throughput genotyping methods created
A. Gurgul, I. Jasielczuk, E. Semik-Gurgul, K. Pawlina-Tyszko, M. Stefaniuk-Szmukier, T. Szmatoła, G. Polak, I. Tomczyk-Wrona, M. Bugno-Poniewierska   +8 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Signatures of the excitonic memory effects in four-wave mixing processes in cavity polaritons

, 2000
We report the signatures of the exciton correlation effects with finite memory time in frequency domain degenerate four-wave mixing (DFWM) in semiconductor microcavity.
A.L. Ivanov, B.F. Feuerbacher, C. Sieh, C. Weisbuch, D.J. Lovering, E. Hanamura, E.J. Mayer, G.M. Gale, H. Haug, H. Suzuura, H. Wang, J. Inoue, L.A. Lugiato, L.J. Sham, M. Itoh, M. Kuwata-Gonokami, M. Kuwata-Gonokami, M. Shirane, M.Z. Maialle, Makoto Kuwata-Gonokami, O. Akimoto, P. Kner, P. Kner, Q. Fu, T. Aoki, T. Saiki, T. Saiki, Th. Ostrreich, Th. Ostrreich, V. Chernyak, W. Schaefer, X. Fan, Y. Nozue, Yu. P. Svirko, Yu.P. Svirko   +34 more
core   +1 more source