Results 31 to 40 of about 16,978 (266)

Copper‐based nanocatalysts toward chemoselective hydrogenation reaction

cMat
Cu‐based catalysts are widely used in various heterogeneous catalytic reaction systems, the precise control of their electronic structure is an intrinsic requirement for the rational design of metal catalysts, and it is also an important basis for ...
Hui Guo, Ling‐Jun Pei, Shao‐Lei Xie, Meng‐Qi Shen, Yong Yang, Hu Liu   +5 more
doaj   +1 more source

Breaking scaling relationships in alkynol semi-hydrogenation by manipulating interstitial atoms in Pd with d-electron gain

Nature Communications, 2022
Circumventing the linear scaling relationship in the semi-hydrogenation is challenging. Here the authors report a method for breaking the scaling relationships using ordered mesoporous carbon-supported Pd nanocatalysts with d-electron gain by p-block ...
Yang Yang, Xiaojuan Zhu, Lili Wang, Junyu Lang, Guohua Yao, Tian Qin, Zhouhong Ren, Liwei Chen, Xi Liu, Wei Li, Ying Wan   +10 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Synthetic Strategies of Supported Pd-Based Bimetallic Catalysts for Selective Semi-Hydrogenation of Acetylene: A Review and Perspectives

Molecules, 2023
Selective semi-hydrogenation of acetylene is an extremely important reaction from both industrial and theoretical perspectives. Palladium, due to its unique chemical and physical properties, is the most active and currently irreplaceable metal for this ...
Xinxiang Cao, Ben W.-L. Jang, Jiaxue Hu, Lei Wang, Siqi Zhang   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Copper-based heterogeneous catalysts for sustainable CO

Chemical Engineering Journal. Green and Sustainable
Thermo-catalytic selective CO 2 hydrogenation to produce valuable fuel, ethanol is a promising approach to mitigate greenhouse gas emissions as well as producing sustainable fuel. Even though CO 2 has been successfully converted into high-yield C1 fuels;
Sujit Kumar Guchhait, Rajendra Kumar Saini, Partha Mukherjee, Sunaina   +3 more
doaj   +1 more source