Results 81 to 90 of about 78,923 (333)

Gas-liquid hydrodynamics in Taylor Flows with complex liquids [PDF]

, 2010
Universitá di Pisa Facoltá di Ingegneria Dipartimento di Ingegneria Chimica, Chimica Industriale e Scienza dei Materiali Relazione di tirocinio in Ingegneria Chimica Gas-liquid hydrodynamics in Taylor Flows with complex liquids Il candidato: Federico ...
ALBERINI, FEDERICO
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Local generation of hydrogen for enhanced photothermal therapy. [PDF]

, 2018
By delivering the concept of clean hydrogen energy and green catalysis to the biomedical field, engineering of hydrogen-generating nanomaterials for treatment of major diseases holds great promise.
Chen, Danyang, Chen, Qian, Gu, Zhen, He, Qianjun, Jin, Zhaokui, Lu, Xifeng, Meng, Jin, Yang, Tian, Zhao, Penghe   +8 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Proton-Electron Hyperfine Coupling Constants of the Chlorophyll a Cation Radical by ENDOR Spectroscopy [PDF]

, 1977
In this paper we describe the assignment of the major coupling constants in monomer chlorophyll a cation free radical by ENDOR spectroscopy. To facilitate chemical manipulation methylpyrochlorophyllide a has been used as a stand-in, and a suite of six ...
Katz, J. J., Norris, J. R., Scheer, Hugo
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Novel Turn-On Fluorescent Probe Based on Naphthalimide for Highly Selective and Sensitive Detection of Hydrogen Sulfide in Solution and Gas [PDF]

, 2023
Wu Zhou, Min Peng, Qingxiang Liang, Aibin Wu, Wen‐Ming Shu, Weichu Yu   +5 more
openalex   +1 more source

Recyclable Platinum Nanocatalyst for Nitroarene Hydrogenation: Gum Acacia Polymer-Stabilized Pt Nanoparticles with TiO₂ Support

ChemEngineering
Platinum has emerged as an optimal catalyst for the selective hydrogenation of nitroarenes owing to its high hydrogenation activity, selectivity, and stability.
Supriya Prakash, Selvakumar Ponnusamy, Jagadeeswari Rangaraman, Kundana Nakkala, Putrakumar Balla   +4 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Dialing in single-site reactivity of a supported calixarene-protected tetrairidium cluster catalyst. [PDF]

, 2017
A closed Ir4 carbonyl cluster, 1, comprising a tetrahedral metal frame and three sterically bulky tert-butyl-calix[4]arene(OPr)3(OCH2PPh2) (Ph = phenyl; Pr = propyl) ligands at the basal plane, was characterized with variable-temperature 13C NMR ...
Ertler, Daniel, Gates, Bruce C, Katz, Alexander, Okrut, Alexander, Palermo, Andrew, Solovyov, Andrew   +5 more
core   +2 more sources