Results 61 to 70 of about 65,546 (303)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Review of catalytic systems and thermodynamics for the Guerbet condensation reaction and challenges for biomass valorization [PDF]
, 2015 The Guerbet condensation reaction is an alcohol coupling reaction that has been known for more than a century. Because of the increasing availability of bio-based alcohol feedstock, this reaction is of growing importance and interest in terms of value ...
Gabriels, D +4 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Catalysis Communications, 2021 Bimetallic Ni-Cu/SiO2 catalysts with different Cu loading (2–5 wt%) were developed for liquid phase selective hydrogenation of furfural to furfuryl alcohol.
Patcharaporn Weerachawanasak +5 more
doaj +1 more source
The Success Story of Gold-Based Catalysts for Gas- and Liquid-Phase Reactions: A Brief Perspective and Beyond [PDF]
, 2019 Gold has long held the fascination of mankind. For millennia it has found use in art, cosmetic metallurgy and architecture; this element is seen as the ultimate statement of prosperity and beauty.
Ivanova, Svetlana +4 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Facile Protocol for Water-Tolerant “Frustrated Lewis Pair”-Catalyzed Hydrogenation [PDF]
, 2015 Despite rapid advances in the field of metal-free, “frustrated Lewis pair” (FLP)-catalyzed hydrogenation, the need for strictly anhydrous reaction conditions has hampered wide-scale uptake of this methodology.
Ashley, Andrew E. +5 more
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Selective ensembles in supported palladium sulfide nanoparticles for alkyne semi-hydrogenation
Nature Communications, 2018 Developing robust catalysts for alkyne semi-hydrogenation remains a challenge. Here, the authors introduce a scalable protocol to prepare crystal phase and orientation controlled Pd3S nanoparticles supported on carbon nitride, exhibiting unparalleled ...
Davide Albani +6 more
doaj +1 more source
Catalytic Performance of Ru/polymer Catalyst in the Hydrogenation of Furfural to Furfuryl Alcohol
Chemical Engineering Transactions, 2020 Furfural (FF) is one of the main components of bio-oil obtained by the treatment of lignocellulose biomass. Furfural alcohol (FA) as the main product of the selective FF hydrogenation is a source of value-added chemicals.
Mikhail Sulman +8 more
doaj +1 more source