Results 81 to 90 of about 1,055,415 (308)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
, 2009 A series of Ru/Al2O3/cordierite monolithic catalysts were prepared and characterized by BET, XRD, TPR, TEM and SEM-EDAX. The catalytic performances in selective hydrogenation of benzene to cyclohexene were investigated in a continuous fixed-bed reactor ...
Zhao, Yujun +4 more
core +1 more source
ChemEngineeringPlatinum has emerged as an optimal catalyst for the selective hydrogenation of nitroarenes owing to its high hydrogenation activity, selectivity, and stability.
Supriya Prakash +4 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
RuAl2O3—ZrO2—NiOcordierite monolithic catalysts for selective hydrogenation of benzene
, 2013 RuAl2O3—ZrO2—NiOcordierite monolithic catalysts for selective hydrogenation of ...
王铭浩, 苏宏久, 王树东, 周谨
core
Synthesis of Co-Sn intermetallic nanocatalysts toward selective hydrogenation of citral
, 2016 In this work, three supported Co-Sn intermetallic compound (IMC) catalysts (Co2.9Sn2, CoSn and CoSn2) with a particle size of similar to 20 nm were prepared via a facile hydrotalcite approach, and their catalytic performances were evaluated in the ...
Zhang, Shitong +6 more
core +1 more source