Results 41 to 50 of about 56,592 (279)
Targeted and untargeted selections including domestication and breeding efforts can reduce genetic diversity in breeding germplasm and create selective sweeps in crop genomes.
Aamir Saleem +8 more
doaj +1 more source
SWEEPFINDER2: Increased sensitivity, robustness, and flexibility
SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the ...
DeGiorgio, Michael +4 more
core +1 more source
Calculation of the potential field in nerve stimulation using a multigrid method [PDF]
This paper deals with the first step in the modeling of newe stimulation: the calculation of the potential field in a 3D volume conductor model of the nerve. surroundings and electrodes.
Goodall, Eleanor V. +4 more
core +3 more sources
Fixation probability for competing selective sweeps
We consider a biological population in which a beneficial mutation is undergoing a selective sweep when a second beneficial mutation arises at a linked locus and we investigate the probability that both mutations will eventually fix in the population.
Cuthbertson, Charles +2 more
openaire +5 more sources
Robust forward simulations of recurrent hitchhiking [PDF]
Evolutionary forces shape patterns of genetic diversity within populations and contribute to phenotypic variation. In particular, recurrent positive selection has attracted significant interest in both theoretical and empirical studies.
Hernandez, Ryan D. +1 more
core +2 more sources
Effects of Linked Selective Sweeps on Demographic Inference and Model Selection [PDF]
Abstract The availability of large-scale population genomic sequence data has resulted in an explosion in efforts to infer the demographic histories of natural populations across a broad range of organisms. As demographic events alter coalescent genealogies, they leave detectable signatures in patterns of genetic variation within and ...
Schrider, Daniel R. +2 more
openaire +2 more sources
Rapid adaptation of a polygenic trait after a sudden environmental shift
Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core +1 more source
Scans for signatures of selection in Russian cattle breed genomes reveal new candidate genes for environmental adaptation and acclimation [PDF]
Domestication and selective breeding has resulted in over 1000 extant cattle breeds. Many of these breeds do not excel in important traits but are adapted to local environments.
A Talenti +108 more
core +5 more sources
Pervasive selective sweeps across human gut microbiomes
AbstractThe human gut microbiome is composed of a highly diverse consortia of species which are continually evolving within and across hosts. The ability to identify adaptations common to many human gut microbiomes would not only reveal shared selection pressures across hosts, but also key drivers of functional differentiation of the microbiome that ...
Wolff, Richard, Garud, Nandita R.
openaire +2 more sources
A Selective Sweep across Species Boundaries in Drosophila [PDF]
Adaptive mutations that accumulate during species divergence are likely to contribute to reproductive incompatibilities and hinder gene flow; however, there may also be a class of mutations that are generally advantageous and can spread across species boundaries.
Brand, Cara L. +3 more
openaire +3 more sources

