Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation
The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Thomas Fischer, Rainer Riedl
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Toxicity of organic supplies for the egg parasitoid Telenomus podisi [PDF]
Toxicity (dosage per hectare) of: 1) Baculovirus anticarsia 140x109 cpi; 2) Bacillus thuringiensis 16.8g; 3) Azadirachtin-A, azadirachtin-B, nimbina and salamina 9.6 ppm; 4) Rotenoids 4 liters; 5) Nitrogen 1.3%, phosphorus 3.0% and total organic carbon 8.
Débora Mello da Silva +1 more
doaj
O controle do bicho-mineiro-do-cafeeiro Leucoptera coffeella (Guérin-Mèneville & Perrottet, 1842) é realizado por meio de inseticidas de amplo espectro de ação, capazes de causar desequilíbrios biológicos, sendo importante a busca por produtos que ...
José Marcos Angélico de Mendonça +4 more
doaj +1 more source
Dynamic hydration valve controlled ion permeability and stability of NaK channel [PDF]
The K^+^, Na^+^, Ca^2+^ channels are essential to neural signalling, but our current knowledge at atomic level is mainly limited to that of K^+^ channels.
Rong Shen, Wanlin Guo, Wenyu Zhong
core +1 more source
Optical Excitation of a Nanoparticle Cu/p-NiO Photocathode Improves Reaction Selectivity for CO₂ Reduction in Aqueous Electrolytes [PDF]
We report the light-induced modification of catalytic selectivity for photoelectrochemical CO₂ reduction in aqueous media using copper (Cu) nanoparticles dispersed onto p-type nickel oxide (p-NiO) photocathodes.
Atwater, Harry A. +5 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
SYNTHESIS AND CHARACTERIZATION OF POLYIMIDEZEOLITE MIXED MATRIX MEMBRANE FOR BIOGAS PURIFICATION [PDF]
Biogas has become an attractive alternative energy source due to the limitation of energy from fossil. In this study, a new type of mixed matrix membrane (MMM) consisting of polyimide-zeolite was synthesized and characterized for biogas purification ...
Budiyono, Budiyono +4 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Editorial: Heterogeneous Catalysis for Methane Activation
Juanjuan Liu +4 more
doaj +1 more source

