Results 71 to 80 of about 499,252 (266)
The development of miniaturized sensors has become relevant for the detection of chemical/biological substances, since they use and detect low concentrations, such as flocculants based on amines for the mining industry.
Débora Ely Medeiros Ferreira +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Synthesis and Anticancer Potential of New Benzimidazole Theranostic
A series of novel benzimidazole analogs is designed, synthesized, and screened against a panel of selected cancer cell lines, including H103 (oral squamous cell carcinoma, OSCC), H314 (OSCC), and HCT116 (colorectal carcinoma). Structural characterization
Sahani Sandalima Uthumange +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Advances in the understanding of selective CO2 reduction catalysis
The electrochemical synthesis for value‐added chemicals and fuels via carbon dioxide reduction reaction (CO2RR) offers an effective route to close the anthropogenic carbon cycle and store renewable energy.
Ruihu Lu, Yan Liu, Ziyun Wang
doaj +1 more source
Heavy metal pollution, especially from Pb(II) and Cd(II), poses significant risks due to its persistence and bioaccumulation potential. Traditional removal methods face challenges like high costs and secondary pollution.
Chunxiao Wang +10 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Electrochemical CO2 reduction (CO2RR) presents a sustainable approach to converting greenhouse gases into valuable chemicals. However, achieving precise product selectivity remains challenging.
Chengxi Yao +6 more
doaj +1 more source
Towards Enhanced Gas Sensor Performance with Fluoropolymer Membranes
In this paper we report on how to increase the selectivity of gas sensors by using fluoropolymer membranes. The mass transport of polar and non-polar gases through a polymer membrane matrix was studied by systematic selection of polymers with different ...
Thorsten Graunke +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

