Results 51 to 60 of about 2,788,136 (316)
Sensitivity-Selectivity Trade-Offs in Surface Ionization Gas Detection
Nanomaterials, 2018 Surface ionization (SI) provides a simple, sensitive, and selective method for the detection of high-proton affinity substances, such as organic decay products, medical and illicit drugs as well as a range of other hazardous materials. Tests on different
Gerhard Müller +5 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Oncolytic Viruses—Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer
Frontiers in Oncology, 2017 Oncolytic viruses (OVs) are an emerging treatment option for many cancer types and have recently been the focus of extensive research aiming to develop their therapeutic potential.
Anwen Howells +5 more
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Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
Angewandte Chemie, 2009 The study of biomolecules in their native environments is a challenging task because of the vast complexity of cellular systems. Technologies developed in the last few years for the selective modification of biological species in living systems have ...
Ellen M. Sletten, C. Bertozzi
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
ХРАНИТЕЛЕН СПЕКТЪР И СЕЛЕКТИВНОСТ НА ХРАНЕНЕ НА ЛИЧИНКИТЕ НА БЯЛАТА РИБА (SANDER LUCIOPERCA L.)
Животновъдни науки, 2014 Diet and growth of pikeperch fry (Sander lucioperca) reared in fish pond was investigated for period of 32 days. In body size about 11.0 mm main food items are zooplankton representatives of the genus Bosmina and partly by Copepoda.
ДОЙЧИН ТЕРЗИЙСКИ +3 more
doaj
Nature Communications, 2017 Direct electrochemical reduction of CO2 to fuels and chemicals using renewable electricity has attracted significant attention partly due to the fundamental challenges related to reactivity and selectivity, and partly due to its importance for industrial
W. Ju +9 more
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Zinc binding groups for histone deacetylase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Zinc binding groups (ZBGs) play a crucial role in targeting histone deacetylase inhibitors (HDACIs) to the active site of histone deacetylases (HDACs), thus determining the potency of HDACIs.
Lei Zhang +4 more
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Intradural Spinal Cord Stimulation: Performance Modeling of a New Modality
Frontiers in Neuroscience, 2019 Introduction: Intradural spinal cord stimulation (SCS) may offer significant therapeutic benefits for those with intractable axial and extremity pain, visceral pain, spasticity, autonomic dysfunction and related disorders.
David J. Anderson +9 more
doaj +1 more source