Results 51 to 60 of about 834,885 (307)
SELECTION DIFFERENTIALS AND SELECTION COEFFICIENTS [PDF]
Genetics, 1978 ABSTRACT Proof is offered that s ≃ ig for all forms of selection where fitness is a nondecreasing function of a normally distributed phenotype (called fitness potential); s is selection coefficient, i is standard selection differential, and g is standard differential effect of a locus genotype.
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Sensitivity-Selectivity Trade-Offs in Surface Ionization Gas Detection
Nanomaterials, 2018 Surface ionization (SI) provides a simple, sensitive, and selective method for the detection of high-proton affinity substances, such as organic decay products, medical and illicit drugs as well as a range of other hazardous materials. Tests on different
Gerhard Müller +5 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Oncolytic Viruses—Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer
Frontiers in Oncology, 2017 Oncolytic viruses (OVs) are an emerging treatment option for many cancer types and have recently been the focus of extensive research aiming to develop their therapeutic potential.
Anwen Howells +5 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Theoretical Studies of Reactivity and Selectivity in some organic Reactions
, 2010 Some organic reactions with biological or commercial interest have been studied by using reactivity and selectivity indices proposed in the density functional theory.
Meneses Olmedo, Lorena Maribel
core +1 more source
ХРАНИТЕЛЕН СПЕКТЪР И СЕЛЕКТИВНОСТ НА ХРАНЕНЕ НА ЛИЧИНКИТЕ НА БЯЛАТА РИБА (SANDER LUCIOPERCA L.)
Животновъдни науки, 2014 Diet and growth of pikeperch fry (Sander lucioperca) reared in fish pond was investigated for period of 32 days. In body size about 11.0 mm main food items are zooplankton representatives of the genus Bosmina and partly by Copepoda.
ДОЙЧИН ТЕРЗИЙСКИ +3 more
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Zinc binding groups for histone deacetylase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Zinc binding groups (ZBGs) play a crucial role in targeting histone deacetylase inhibitors (HDACIs) to the active site of histone deacetylases (HDACs), thus determining the potency of HDACIs.
Lei Zhang +4 more
doaj +1 more source