Results 51 to 60 of about 732,422 (217)

Highly Diastereo- and Enantioselective Allylboration of Aldehydes using alpha-Substituted Allyl/Crotyl Pinacol Boronic Esters via in Situ Generated Borinic Esters [PDF]

, 2013
Readily available, alpha-substituted allyl/crotyl pinacol boronic esters often give low E/Z selectivity (with Z favored) in reactions with aldehydes. We found that addition of nBuLi to the pinacol boronic ester followed by trapping of the alkoxide with ...
Jack L.‐Y. Chen, Aggarwal, Varinder K., Chen, Jack L. -Y., Scott, Helen K., Christine L. Willis, Willis, Christine L., Helen K. Scott, Hesse, Matthew J., Matthew J. Hesse, Jack L.-Y. Chen, Varinder K. Aggarwal   +10 more
core   +1 more source

Structure-based discovery of a new selectivity-enabling motif for the FK506-binding protein 51

, 2023
In recent years the selective inhibition of FKBP51 has emerged as a possible treatment for chronic pain, obesity-induced diabetes, or depression. All currently known advanced FKBP51-selective inhibitors, including the widely used SAFit2, contain a ...
Felix, Hausch, Mathias, Schmidt, Fabian, Knaup, Margherita , Springer, Saskia, Wedel, Carlo, Walz, Marco, Sisignano, Wisley, Sugiarto, Thomas, Geiger, Christian , Meyners   +9 more
core   +1 more source

Preparation of Covalent-Ionically Cross-Linked UiO-66-NH2/Sulfonated Aromatic Composite Proton Exchange Membranes With Excellent Performance

Frontiers in Chemistry, 2020
Metal-organic frameworks (MOFs), as newly emerging filler materials for polyelectrolytes, show many compelling intrinsic features, such as variable structural designability and modifiability of proton conductivity.
Penglun Zheng, Quanyi Liu, Donghui Wang, Zekun Li, Yawei Meng, Yun Zheng   +5 more
doaj   +1 more source

Natural selection. III. Selection versus transmission and the levels of selection* [PDF]

Journal of Evolutionary Biology, 2011
AbstractGeorge Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission. In this article, I extend Williams’ approach to show that the ratio of selection bias to transmission bias provides a unifying framework for diverse ...
openaire   +3 more sources

Ion-imprinted polyaniline-based polymer for selective electrochemical detection of cadmium

Journal of Electrochemical Science and Engineering
An electrochemical sensor based on ion-imprinted functionalized polyaniline has been fabricated and tested for the electrochemical sensing of cadmium in aqueous solution. The synthesis of the polymer was started by copolymerizing anthranilic acid and 2-
Eldhose V. Varghese, Roshny Roy, Carsten Schwandt, Praveen C. Ramamurthy, Alex Joseph   +4 more
doaj   +1 more source

Recent Advances in Fluorescent Arylboronic Acids for Glucose Sensing

Biosensors, 2013
Continuous glucose monitoring (CGM) is crucial in order to avoid complications caused by change in blood glucose for patients suffering from diabetes mellitus.
Jon Stefan Hansen, Jørn Bolstad Christensen   +1 more
doaj   +1 more source

Vibrational and Resistance Responses for Ether-Amine Solutions of the Buckypaper-Based Chemiresistor Sensor

Nanomaterials
The development of miniaturized sensors has become relevant for the detection of chemical/biological substances, since they use and detect low concentrations, such as flocculants based on amines for the mining industry.
Débora Ely Medeiros Ferreira, Paula Fabíola Pantoja Pinheiro, Luiza Marilac Pantoja Ferreira, Leandro José Sena Santos, Rosa Elvira Correa Pabón, Marcos Allan Leite Reis   +5 more
doaj   +1 more source

Risk-adjusted performance, selectivity, timing ability and performance persistence of Hong Kong mutual funds [PDF]

, 2007
This paper examines the performance of thirty Hong Kong mutual funds during the period from August 1995 to July 2005. The issues of risk-adjusted performance, selectivity, timing ability and performance persistence are addressed.
Kuang, Y, Abdel-Kader, MG
core   +1 more source

Deciphering the selectivity of CBL-B inhibitors using all-atom molecular dynamics and machine learning

, 2023
We employ a combination of accelerated molecular dynamics and machine learning techniques to unravel the dynamic characteristics of CBL-B and C-CBL, and how their configurational changes conferring the binding affinity and selectivity of their ligands ...
Weiqiang, Fu, Yang, Wang, yingsheng, zhang, Haolin, Du, Feng, Zhou   +4 more
core   +1 more source

Synthesis and Anticancer Potential of New Benzimidazole Theranostic

ChemistryOpen
A series of novel benzimidazole analogs is designed, synthesized, and screened against a panel of selected cancer cell lines, including H103 (oral squamous cell carcinoma, OSCC), H314 (OSCC), and HCT116 (colorectal carcinoma). Structural characterization
Sahani Sandalima Uthumange, Muhammad Azri Faiz bin Abdul Zaki, Keng Yoon Yeong   +2 more
doaj   +1 more source