Results 171 to 180 of about 97,028 (300)

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro, Rosângela Mayer Gonçalves, Marcelle Gomes Pegurier, Isabelle Amorim, Alexandre Malta Rossi, Leandra Santos Baptista   +5 more
wiley   +1 more source

Comprehensive Analysis of Selenium Metabolism and Selenoproteins-Associated Gene Signatures in Ulcerative Colitis. [PDF]

J Inflamm Res
Gao C, Wang J, Dai S, Wang D, Wang J.
europepmc   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

Antioxidant status, cytokine level, immunocompetence, Hsp70 mRNA expression, and selenium metabolism of goats fed higher selenium under heat stress conditions. [PDF]

Sci Rep
Aderao GN, Jadhav SE, Lokesha E, Pattanaik AK, Chaudhary P, Ramakrishnan S, Dutta N, Singh G, Gupta SK.   +8 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Peripheral Lymphocytes in Primary Liver Cancers: Elevated NK and CD8+ T Cells and Dysregulated Selenium Metabolism. [PDF]

Biomolecules
Zhou C, Lu Z, Sun B, Yi Y, Zhang B, Wang Z, Qiu SJ.   +6 more
europepmc   +1 more source

Effect of Zinc Oxide Nanoparticles From Infant Formula Milk Powder on Colon Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Zinc is an essential trace element that participates in numerous metabolic processes; however, excessive exposure may interfere with the absorption of other metals, such as copper. In recent years, nanotechnology has experienced rapid growth, and zinc oxide nanoparticles (ZnO NPs) have garnered significant attention due to their versatile ...
Gloria Salinas‐Lucero, Karla Juarez‐Moreno, Rafael Vazquez‐Duhalt   +2 more
wiley   +1 more source

Glycemic Regulation and Renal Function by Heavy Metal Exposure: A Cross‐Sectional Analysis on Cement Plant Workers

Journal of Applied Toxicology, EarlyView.
ABSTRACT Heavy metal exposure is known to have various effects on renal function and blood glucose regulation. The main objective of this study was to evaluate the effects of cement dust and some metal (cadmium, manganese, nickel, and zinc) exposure on blood glucose and renal function parameters in male cement plant workers.
Duygu Seyhan Erdoğan, Fatma Bozdag, Fatıma Betül Topcu, Osman Burak Demirbas, Sultan Pinar Cetintepe, Mustafa Necmi Ilhan   +5 more
wiley   +1 more source

Impact of fortifiers on donor milk nutrient composition: An experimental study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Preterm infants frequently require human milk fortification to meet their unique nutrients requirements. How commercial fortifiers change essential macronutrients and micronutrients in donor human milk has not been well‐studied. Methods Our sampling frame included milk from approved United States milk bank donors (n = 400), measured
Kimberly Mansen, Hannah Sanders, Sarah N. Taylor, Raven Dunstan, Kiersten Israel‐Ballard, Maryanne T. Perrin   +5 more
wiley   +1 more source

Selenium biofortification and phytoremediation phytotechnologies: A review [PDF]

, 2017
Pilon-Smits, Elizabeth A. H., Schiavon, Michela   +1 more
core   +1 more source