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Selenium Metabolism and Mechanisms of Cancer Prevention
2001It has been 50 years since the surprising discovery in 1949 that selenium (Se) had cancer preventing properties in animals given a chemical carcinogen (1). Numerous studies have confirmed the anticarcinogenic effects of supranutritional levels of Se in animals and more recently in humans given supplemental Se, as described by Combs (2).
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[Selenium in peroxide metabolism].
Medizinische Klinik (Munich, Germany : 1983), 1997Out of the growing number of so far known mammalian selenoproteins four are peroxidases. Their common catalytic mechanism involves redox shuttling of a selenocysteine residue in the active site, where it forms a characteristic catalytic triad with hydrogen-bonded tryptophan and glutamine residues.
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The role of hypoxia in selenium metabolism
Biochemical Pharmacology, 1987P, Garberg, J, Högberg
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STUDIES ON SELENIUM METABOLISM: THE DISTRIBUTION OF SELENIUM IN THE TISSUES OF THE MOUSE
The Journal of Pharmacology and Experimental Therapeutics, 1955M, HEINRICH, F E, KELSEY
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Essentiality and Metabolic Functions of Selenium
Medical Clinics of North America, 1976openaire +2 more sources