Selenomethionine metabolism and its toxicity in yeast
Biomolecular Concepts, 2013 The importance of selenium for organisms can be explained by its existence as selenocysteine in the catalytic centers of glutathione peroxidase and thioredoxin reductase. Another selenoamino acid, selenomethionine, is the major form of selenium in foods,
Toshihiko Kitajima, Yasunori Chiba
exaly +4 more sources
Selenomethionine as a dual-mechanism ferroptosis inhibitor: selenium-supply-driven GPX4 biosynthesis beyond transsulfuration and reductive-capacity-mediated ROS scavenging independent of GPX4 activity [PDF]
Cell Death and DiseaseFerroptosis is an iron-dependent form of nonapoptotic cell death driven by lipid peroxidation. The selenium-dependent glutathione peroxidase 4 (GPX4) serves as the central regulator of ferroptosis through enzymatic reduction of phospholipid ...
Chaoyi Xia +7 more
doaj +2 more sources
Administration of selenomethionine in combination with serine benefits diabetes via gut microbiota
Frontiers in Microbiology, 2022 Either selenium or serine could modulate glucose homeostasis, however, whether there are synergistic effects of selenium with serine on diabetes remains to be unknown.
Xiaoyan Cui, Yuexi Yang
exaly +3 more sources
Elucidating the Effects of Selenium Enrichment on the Structure and Antioxidant Properties of Selenium-Containing Proteins in Yeast Cells [PDF]
AntioxidantsSelenium (Se) enrichment in yeast represents a promising strategy for producing organic Se with high bioavailability. However, a systematic understanding of how Se incorporation alters intact protein structure and function across diverse strains remains ...
Lixia He +5 more
doaj +2 more sources
Relative bioavailability of selenium yeast, selenomethionine, hydroxyl-selenomethionine and nano-selenium for broilers. [PDF]
Front Vet SciSelenium (Se) is an essential trace element for humans and animals. Development and application of new forms of Se sources with lower toxicity and higher bioavailability has been attracting more attention. However, the bioavailabilities of Se from several new Se sources for broilers remain unclear.
Liu G +9 more
europepmc +3 more sources
Ecotoxicology and Environmental Safety, 2022 Ammonia has been reported to have a variety of toxicity to aquatic animals, farm animals and humans. However, its potential toxicity on the intestines remains unknown. L-selenomethionine is one of the important organic selenium sources.
Xinxin Zhang +4 more
doaj +1 more source
Influence of selenomethionine and omega-3 fatty acid on serum mineral profile and nutrient utilization of broiler chicken [PDF]
Veterinary World, 2015 Aim: This study was conducted to investigate the effect of selenomethionine and omega-3 fatty acid on serum mineral profile and nutrient utilization of broiler chicken.
Pankaj Kumar +3 more
doaj +1 more source
Shipin gongye ke-ji, 2023 Objective: To screen and optimize the method for preparing three-dimensional structural samples of restriction endonuclease Bsa I. Methods: In this study, the Escherichia coli expression system was employed to express the Bsa I protein and its ...
Hai ZHU +8 more
doaj +1 more source
Integrated Environmental Assessment and Management, EarlyView., 2023 Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves +6 more
wiley +1 more source
Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. [PDF]
PLoS ONE, 2015 Ochratoxin A (OTA), a mycotoxin, is a potent nephrotoxin in humans and animals. Selenium (Se) is an essential micronutrient for humans and animals, and plays a key role in antioxidant defense.
Fang Gan +4 more
doaj +1 more source