Results 81 to 90 of about 18,777 (226)

Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages

Frontiers in Microbiology, 2020
Inflammation is the hallmark of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli-induced bovine mastitis. Organic selenium can activate pivotal proteins in immune responses and regulate the immune system.
Cuicui Zhuang, Gang Liu, Herman W. Barkema, Man Zhou, Siyu Xu, Sadeeq ur Rahman, Yongxia Liu, John P. Kastelic, Jian Gao, Bo Han   +9 more
doaj   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, Volume 13, Issue 21, 13 April 2026.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

METABOLISM AND MECHANISM OF TOXICITY OF SELENIUM-CONTAINING SUPPLEMENTS USED FOR OPTIMIZING HUMAN SELENIUM STATUS

Тонкие химические технологии, 2019
The work presents a review devoted to the metabolism and the mechanism of toxicity of seleniumcontaining supplements: elemental selenium, sodium selenite, diacetophenonyl selenide, selenopyrane, ebselen, dimethyl dipyrasolyl selenide and selenium ...
P. A. Poluboyarinov, D. G. Elistratov, V. I. Shvets   +2 more
doaj   +1 more source

Inter-individual variation in nucleotide excision repair in young adults: effects of age, adiposity, micronutrient supplementation and genotype [PDF]

, 2009
Nucleotide excision repair (NER) is responsible for repairing bulky helix-distorting DNA lesions and is essential for the maintenance of genomic integrity.
Alison Spiers, Ann K. Daly, Brian Burtle, Elizabeth A. Williams, Fiona Caple, Gaivão, John C. Mathers, John E. Hesketh, John Tyson, Qiao, Tomasetti, Wei   +11 more
core   +1 more source

Crystal structures of Fsc1, a novel autophagy factor that mediates autophagosome–vacuole fusion in fission yeast

Acta Crystallographica Section D, Volume 82, Issue 4, Page 358-369, April 2026.
Crystal structures of the autophagy protein Fsc1 reveal conserved fasciclin features and a stable dimer interface that illuminate its possible role as a scaffold in autophagosome–vacuole membrane fusion.Fsc1 is a recently identified autophagy factor in the fission yeast Schizosaccharomyces pombe that is implicated in the autophagosome–vacuole fusion ...
Chidiogo Azuka, Jian Liu, Xiangshu Jin
wiley   +1 more source

Selenium and selenium species in feeds and muscle tissue of Atlantic salmon [PDF]

, 2018
Selenium (Se) is an essential element for animals, including fish. Due to changes in feed composition for Atlantic salmon (Salmo salar), it may be necessary to supplement feeds with Se.
Amlund, Heidi, Berntssen, Marc H.G., Sele, Veronika, Sloth, Jens Jørgen, Ørnsrud, Robin   +4 more
core   +2 more sources

OsPT4 Facilitates Selenomethionine Transport and Biosynthesis to Enhance Seed Accumulation in Rice: Molecular Mechanisms and Biotechnological Potential

Plant Biotechnology Journal, Volume 24, Issue 4, Page 1992-2008, April 2026.
ABSTRACT Selenium (Se) is a vital micronutrient for humans, with important functions for health and anti‐cancer properties. Organic Se shows higher antioxidant activity and much lower toxicity compared to inorganic Se, making it safer for use. Selenomethionine (SeMet) is one of the primary forms of organic Se.
Yang Yang, Lijuan Sun, Jia Wei, Fang Zhang, Shiyan Yang, Jiarui Zhang, Qin Qin, Jun Wang, Guohua Xu, Shubin Sun, Yafei Sun, Yong Xue   +11 more
wiley   +1 more source

Foliar Application of Nano‐Selenium Enhances Tea Quality and Selenium Biofortification by Promoting Theanine Synthesis and Nitrogen Metabolism

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2300-2311, April 2026.
ABSTRACT Selenium (Se) biofortification improves crops' nutritional value, while nano‐selenium (nano‐Se) offers enhanced bioavailability over traditional Se fertilisers. The quality of tea (Camellia sinensis) depends critically on nitrogen (N) metabolism and amino acid balance, particularly of theanine.
Qingxue Guo, Zhenghao Wu, Yuxin Xiao, Helena Korpelainen, Chunyang Li   +4 more
wiley   +1 more source

Understanding the Redox Biology of Selenium in the Search of Targeted Cancer Therapies

Antioxidants, 2020
Selenium (Se) is an essential trace nutrient required for optimal human health. It has long been suggested that selenium has anti-cancer properties. However, clinical trials have shown inconclusive results on the potential of Se to prevent cancer.
Jeffrey M. Stolwijk, Rohan Garje, Jessica C. Sieren, Garry R. Buettner, Yousef Zakharia   +4 more
doaj   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 1955-1967, 15 March 2026.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source