Selenoprotein P in der kolorektalen Karzinogenese
DNA-Schädigungen durch Sauerstoff-Radikale werden als bedeutende pathogene Faktoren der kolorektalen Karzinogenese angesehen. Als ein antioxidativer Schutzmechanismus im Gastrointestinaltrakt wird u. a. das Selenoprotein P vermutet, dessen mRNA-Expression in Kolonadenomen im Vergleich zu angrenzender gesunder Darmmukosa stark vermindert nachgewiesen ...
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The selenoprotein P 3' untranslated region is an RNA binding protein platform that fine tunes selenocysteine incorporation. [PDF]
Shetty SP, Kiledjian NT, Copeland PR.
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Colorectal cancer mortality is associated with low selenoprotein P status at diagnosis. [PDF]
Brezina S +9 more
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Selenoprotein P Concentrations in the Cerebrospinal Fluid and Serum of Individuals Affected by Amyotrophic Lateral Sclerosis, Mild Cognitive Impairment and Alzheimer's Dementia. [PDF]
Urbano T +10 more
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Glutathione Peroxidase and Selenoprotein P Evaluation in Well-Being Assessment After Total Thyroidectomy. [PDF]
Traini E +6 more
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NRF2-dependent suppression of selenoprotein P expression promotes intracellular selenium metabolic remodeling and upregulation of antioxidant selenoproteins in hepatocellular carcinoma. [PDF]
Arisawa K +7 more
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The Association Between Selenium, Selenoprotein P (SEPP1), Fluid Intelligence, and Exercise in the UK Biobank Cohort. [PDF]
Lehrer S, Rheinstein PH.
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Characterization and Quantification of Selenoprotein P: Challenges to Mass Spectrometry. [PDF]
Lamarche J +3 more
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Indoxyl Sulfate Contributes to Selenium Deficiency and Renal Ferroptosis by Decreasing the Expression of Selenium Transport Protein Selenoprotein P. [PDF]
Nakano T +11 more
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Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo. [PDF]
Bodart-Santos V +5 more
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