Results 1 to 10 of about 12,163 (193)

Overcoming the widespread flaws in the annotation of vertebrate selenoprotein genes in public databases. [PDF]

PLoS Computational Biology
Genome annotations provide the essential framework for genomic analyses, capturing our current knowledge of gene structure and function as inferred from computational predictions and experimental evidence.
Max Ticó, Emerson Sullivan, Roderic Guigó, Marco Mariotti   +3 more
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The mycobacterial selenocysteine machinery: presence and expression [PDF]

RNA Biology
The Mycobacterium genus includes more than 190 species that occupies diverse ecological niches. Some are non-pathogenic and environmental, whereas others cause severe diseases both in humans and animals, e.g. tuberculosis (TB) and leprosy. Selenocysteine
Phani Rama Krishna Behra, Malavika Ramesh, B. M. Fredrik Pettersson, Leif A. Kirsebom   +3 more
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BSepDB: a database of bacterial selenoprotein genes and proteins [PDF]

BMC Genomics
Background Selenoproteins represent a structurally and functionally distinct class of proteins that contribute to cellular antioxidant defense and a wide range of other essential biological processes in specific organisms.
Zhengyue Hong, Hengtao Li, Yan Zhang
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eIF3 Interacts with Selenoprotein mRNAs

Biomolecules, 2022
The synthesis of selenoproteins requires the co-translational recoding of an in-frame UGASec codon. Interactions between the Selenocysteine Insertion Sequence (SECIS) and the SECIS binding protein 2 (SBP2) in the 3′untranslated region (3′UTR) of ...
Hassan Hayek, Gilbert Eriani, Christine Allmang   +2 more
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Alcohol Intake Is Associated With Elevated Serum Levels of Selenium and Selenoprotein P in Humans

Frontiers in Nutrition, 2021
Selenoprotein P is a hepatokine with antioxidative properties that eliminate a physiologic burst of reactive oxygen species required for intracellular signal transduction.
Yuki Isobe, Hiroki Asakura, Hiromasa Tsujiguchi, Takayuki Kannon, Hiroaki Takayama, Yumie Takeshita, Kiyo-aki Ishii, Takehiro Kanamori, Akinori Hara, Tatsuya Yamashita, Atsushi Tajima, Shuichi Kaneko, Hiroyuki Nakamura, Toshinari Takamura   +13 more
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TXNL1 has dual functions as a redox active thioredoxin-like protein as well as an ATP- and redox-independent chaperone

Redox Biology, 2023
TXNL1 (also named TRP32, for thioredoxin related protein of 32 kDa) is a cytosolic thioredoxin-fold protein expressed in all cell types and conserved from yeast to mammals, but with yet poorly known function.
Attila Andor, Mahendravarman Mohanraj, Zsuzsanna Anna Pató, Katalin Úri, Beáta Biri-Kovács, Qing Cheng, Elias S.J. Arnér   +6 more
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Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap). [PDF]

PLoS ONE, 2015
Selenocysteine tRNA 1 associated protein (Trnau1ap) has been characterized as a tRNA[Ser]Sec-binding protein of 43 kDa, hence initially named SECp43. Previous studies reported its presence in complexes containing tRNA[Ser]Sec implying a role of SECp43 as
Yassin Mahdi, Xue-Ming Xu, Bradley A Carlson, Noelia Fradejas, Paul Günter, Doreen Braun, Eileen Southon, Lino Tessarollo, Dolph L Hatfield, Ulrich Schweizer   +9 more
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Increases in Hepatokine Selenoprotein P Levels Are Associated With Hepatic Hypoperfusion and Predict Adverse Prognosis in Patients With Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Although multiorgan networks are involved in the pathophysiology of heart failure (HF), interactions of the heart and the liver have not been fully understood.
Ryohei Takeishi, Tomofumi Misaka, Yasuhiro Ichijo, Shinji Ishibashi, Mitsuko Matsuda, Yukio Yamadera, Himika Ohara, Yukiko Sugawara, Yu Hotsuki, Koichiro Watanabe, Fumiya Anzai, Yu Sato, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Kazuhiko Nakazato, Akiomi Yoshihisa, Yasuchika Takeishi   +18 more
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The algal selenoproteomes

BMC Genomics, 2020
Background Selenium is an essential trace element, and selenocysteine (Sec, U) is its predominant form in vivo. Proteins that contain Sec are selenoproteins, whose special structural features include not only the TGA codon encoding Sec but also the SECIS
Liang Jiang, Yiqian Lu, Lin Zheng, Gaopeng Li, Lianchang Chen, Maona Zhang, Jiazuan Ni, Qiong Liu, Yan Zhang   +8 more
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Relaxation of selective constraints causes independent selenoprotein extinction in insect genomes. [PDF]

PLoS ONE, 2008
BACKGROUND: Selenoproteins are a diverse family of proteins notable for the presence of the 21st amino acid, selenocysteine. Until very recently, all metazoan genomes investigated encoded selenoproteins, and these proteins had therefore been believed to ...
Charles E Chapple, Roderic Guigó
doaj   +1 more source