Results 21 to 30 of about 12,163 (193)
Nature Communications, 2022 Stop codon recoding is a unique mechanism for selenoprotein biogenesis. Here, the authors report regulatory systems for selenoprotein expression during skeletal muscle differentiation by regulating A-to-I RNA editing and stop codon recoding.
Yuta Noda, Shunpei Okada, Tsutomu Suzuki
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BMC Genomics, 2010 Background Computational methods for identifying selenoproteins have been developed rapidly in recent years. However, it is still difficult to identify the open reading frame (ORF) of eukaryotic selenoprotein gene, because the TGA codon for a ...
Jiang Liang, Liu Qiong, Ni Jiazuan
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Modern concept of biological identification of selenoproteins
Regulatory Mechanisms in Biosystems, 2018 Humans possess 25 selenoproteins, approximately half of which are enzymes (selenoenzymes) required for preventing, regulating, or reversing oxidative damage, while others participate in providing calcium metabolism, thyroid hormone maintenance, protein ...
N. V. Stanishevska
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PLoS ONE, 2013 Changes in dietary selenium and selenoprotein status may influence both anti- and pro-cancer pathways, making the outcome of interventions different from one study to another.
Mohamed E Moustafa +13 more
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Selenoproteins and their emerging roles in signaling pathways
Regulatory Mechanisms in Biosystems, 2020 The functional activity of selenoproteins has a wide range of effects on complex pathogenetic processes, including teratogenesis, immuno-inflammatory, neurodegenerative.
N. V. Stanishevska
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Selenoprotein P concentrations and risk of progression from mild cognitive impairment to dementia
Scientific Reports, 2023 There is a growing literature investigating the effects of selenium on the central nervous system and cognitive function. However, little is known about the role of selenoprotein P, the main selenium transporter, which can also have adverse biological ...
Marco Vinceti +8 more
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Beyond antioxidants: Selenium and skeletal muscle mitochondria
Frontiers in Veterinary Science, 2022 The element, Selenium (Se), has an essential nutritive and biological role as a trace mineral known primarily for its vital antioxidant functions as a constituent of the selenoenzyme, glutathione peroxidase.
Lauren T. Wesolowski +2 more
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Frontiers in Neuroscience, 2021 Selenium (Se) and its compounds have been reported to have great potential in the prevention and treatment of Alzheimer’s disease (AD). However, little is known about the functional mechanism of Se in these processes, limiting its further clinical ...
Zhong-Hao Zhang +4 more
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Selenium in Prostate Cancer: Prevention, Progression, and Treatment
Pharmaceuticals, 2023 Selenium, a trace mineral with various biological functions, has become a focal point in prostate cancer research. This review aims to present a comprehensive overview of selenium’s involvement in prostate cancer, covering its impact on prevention ...
Jinjiang Jiang +3 more
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Antioxidants, 2021 This study has determined whether hydroxy-selenomethionine (OH-SeMet) exerts a better protective action on broilers against environmental stress than sodium selenite (SS) or seleno-yeast (SY).
Hua Sun +6 more
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