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Multifaceted arsenal in SELEX nanomedicine
Advances in Colloid and Interface ScienceAptamers, short oligonucleotide sequences that bind specifically to cellular proteins and receptors, are emerging as versatile tools in molecular nanomedicine. Unlike passive tumor targeting via the enhanced permeability and retention (EPR) effect, aptamers enable precise drug delivery, enhancing therapeutic efficacy while minimizing side effects ...
Oishika, Chatterjee +6 more
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Capture-SELEX for aptamer selection: A short review
Talanta, 2021Imran Mahmood Khan, Zhouping Wang
exaly
Accelerating Post-SELEX Aptamer Engineering Using Exonuclease Digestion
Journal of the American Chemical Society, 2021Haixiang Yu, Yi Xiao
exaly
SELEX: Critical factors and optimization strategies for successful aptamer selection
Biotechnology and Applied Biochemistry, 2022Gabriele Gadermaier
exaly
2013
Poster Presentations: Theme 1 - Cancer: abstract no.
Tanner, JA, Kinghorn, A
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Poster Presentations: Theme 1 - Cancer: abstract no.
Tanner, JA, Kinghorn, A
openaire +1 more source
2013
SELEX is a robust technique for identifying nucleic acid aptamers with selectable characteristics. SELEX is a combinatorially tedious exhaustive search system, typically involving up to 1010 possible aptamers. Fully understanding functional relationship(s) between sequence and binding for each SELEX round would be prohibited by the sheer quantity of
Tanner, JA, Kinghorn, AB
openaire +1 more source
SELEX is a robust technique for identifying nucleic acid aptamers with selectable characteristics. SELEX is a combinatorially tedious exhaustive search system, typically involving up to 1010 possible aptamers. Fully understanding functional relationship(s) between sequence and binding for each SELEX round would be prohibited by the sheer quantity of
Tanner, JA, Kinghorn, AB
openaire +1 more source