Results 51 to 60 of about 514,594 (228)

Mechanism assay of interaction between blood vessels-near infrared probe and cell surface marker proteins of endothelial cells

open access: yesMaterials Today Bio, 2022
In vivo blood vessels imaging is crucial to study blood vessels related diseases in real-time. For this purpose, fluorescent based imaging is one of the utmost techniques for imaging a living system. The discovery of a new near-infrared probe (CyA-B2) by
Muhammad Asri Abdul Sisak   +5 more
doaj   +1 more source

Self-assembly of model proteins into virus capsids

open access: yes, 2017
We consider self-assembly of proteins into a virus capsid by the methods of molecular dynamics. The capsid corresponds either to SPMV or CCMV and is studied with and without the RNA molecule inside.
Cieplak, Marek, Wolek, Karol
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Rational design of crystalline two-dimensional frameworks with highly complicated topological structures

open access: yesNature Communications, 2019
Constructing two-dimensional (2D) polymers with complex tessellation patterns is important for the fabrication of advanced materials but achieving such complexity is a great challenge.
Rong-Ran Liang   +8 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

DNA-guided self-assembly in living cells

open access: yesiScience, 2023
Summary: Self-assembly processes exist widely in life systems and play essential roles in maintaining life activities. It is promising to explore the molecular fundamentals and mechanisms of life systems through artificially constructing self-assembly ...
Jinqiao Liu   +4 more
doaj   +1 more source

Reducing facet nucleation during algorithmic self-assembly [PDF]

open access: yes, 2007
Algorithmic self-assembly, a generalization of crystal growth, has been proposed as a mechanism for bottom-up fabrication of complex nanostructures and autonomous DNA computation.
Chen, Ho-Lin   +3 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Creating amphiphilic porosity in two-dimensional covalent organic frameworks via steric-hindrance-mediated precision hydrophilic-hydrophobic microphase separation

open access: yesNature Communications
Creating different pore environments within a covalent organic framework (COF) will lead to useful multicompartment structure and multiple functions, which however has been scarcely achieved.
Shu-Yan Jiang   +7 more
doaj   +1 more source

In situ supramolecular self-assembly for alleviating multidrug resistance in cancer

open access: yesSupramolecular Materials, 2023
Drug resistance is one of the major causes of cancer treatment failures. In recent years, to combat the issue of drug resistance, a large volume of strategies has been established along the development of biomedical nanomaterials.
Jie Zhao   +7 more
doaj   +1 more source

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