Results 71 to 80 of about 5,133,612 (224)

Being bullied during childhood and the prospective pathways to self-harm in late adolescence [PDF]

, 2013
Objective: To assess whether being bullied between 7 and 10 years of age is directly associated with self-harm in late adolescence when controlling for previous exposure to an adverse family environment (domestic violence, maladaptive parenting ...
Lereya, Suzet, Heron, Jon, Wolke, Dieter, Lewis, Glyn, Gunnell, David, Fisher, Helen L; id_orcid, Lereya, Suzet Tanya, Fisher, Helen L, Fisher, Helen L., Winsper, Catherine   +9 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Understanding self-harm in older adults: a qualitative study [PDF]

, 2019
Background Self-harm is the leading risk factor for suicide, with elevated rates reported amongst older populations. This study explores how older adults experience self-harm, identifying factors leading to self-harm.
Lisa Dikomitis, Opeyemi O. Babatunde, M. Isabela Troya, Carolyn A. Chew-Graham, Bernadette Bartlam   +4 more
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Nonsuicidal Self‐Injury in Bangladesh: A Narrative Review

Health Science Reports
Background and Aims Nonsuicidal self‐injury (NSSI) has received global academic attention in recent decades. However, little is known about NSSI behavior in Bangladesh. We aimed to overview NSSI in Bangladesh based on available evidence.
S. M. Yasir Arafat, Bithika Mali, Atiqul Haq Mazumder   +2 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Patient and Public Involvement and Engagement in a doctoral research project exploring self‐harm in older adults

Health Expectations, 2019
Background The contribution of involving patients and public in health research is widely reported, particularly within mental health research. Less is written about such contributions to doctoral research.
M. Isabela Troya, Carolyn A. Chew‐Graham, Opeyemi Babatunde, Bernadette Bartlam, Adele Higginbottom, Lisa Dikomitis   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Teenagers whose friends self-harm are more likely to self-harm.

, 2013
Drug use by friends, low self-esteem, and higher levels of anxiety are all associated with self-harm in teenagers. Having a friend who has self-harmed is one of the most common factors in cases of self-harm among teenagers in Ireland, research has ...

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