Results 81 to 90 of about 5,133,612 (224)

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Learning disability against itself: The self-injury/self-harm conundrum [PDF]

, 2007
This is the author's PDF version of an article published in British journal of learning disabilities© 2008. The definitive version is available at www3.interscience.wiley.comThe article begins with a critical look at the existing literature explaining ...
Lovell, Andy, Andrew Lovell
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Self‐harm‐related mental imagery: A content analysis study of imagery reported by young people referred to mental health services

JCPP Advances
Background Growing evidence suggests that self‐harm‐related mental imagery is involved in the transition from self‐harm ideation to enactment. However, there has been little research on this important phenomenon in adolescent populations.
Karima Susi, Anne Stewart, Rebecca Knowles Bevis, Keith Hawton   +3 more
doaj   +1 more source

Self-harm following release from incarceration: Patterns and measurement issues

International Journal of Population Data Science, 2018
Introduction Despite an elevated prevalence of self-harm in the incarcerated adult population, little is known about patterns of self-harm following release from prison.
Rohan Borschmann, Jesse Young, Stuart Kinner, Matthew Spittal   +3 more
doaj   +1 more source

Striving and competing and its relationship to self-harm in young adults [PDF]

, 2009
Previous research has found that competitive, insecure striving (striving to avoid inferiority) has strong links with mood disorders, self-harm, and appearance anxiety.
McEwan, Kirsten, Gilbert, Paul, Williams, Katie, Katie Williams, Paul Gilbert, Kirsten McEwan   +5 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Self harm: suturing of lips

Revista Española de Sanidad Penitenciaria, 2021
PA Martínez-Carpio, M Álvarez, R Fortea, A Bedoya del Campillo   +3 more
doaj   +1 more source