Results 91 to 100 of about 3,708,862 (338)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Dangers to be avoided in trade acceptance practice,
An address before the convention of the American acceptance council at Detroit, June 9, 1919.Reprint.Mode of access ...
Wills, David C. +1 more
core
Pain, the self and persistence in problem solving [PDF]
Research has suggested that people are motivated to achieve their hopes for the future (hoped-for self) while trying to move away from that which they fear becoming (feared-for self).
Donaldson, Stephen Findlay
core
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Computer self-efficacy and computer anxiety: the effects on technology acceptance in implementing flipped learning approach [PDF]
The technology acceptance model was initially constructed to explain the behavioural intention in adopting and utilising an information system. The model has been widely used to investigate the level of technological innovation adoption, particularly in ...
Abd Rahman, Siti Fatimah +1 more
core +1 more source
Acceptance of aging among Japanese adults aged 20–89
Objectives Acceptance of awareness of age-related change (AARC) is vital for mental health, yet the mechanisms underlying this process remain unclear.
Miho Nakajima, Hikari Kinjo
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Psychological well-being is a system of optimal psychological qualities and states manifested as life strategy and a system of personal attitude to the world and oneself. Self-attitude is an intrapersonal phenomenon of individual projections in the field
Oksana V. Zadorozhnaya +1 more
doaj +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source

