Results 91 to 100 of about 3,708,862 (338)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Dangers to be avoided in trade acceptance practice,

open access: yes, 1919
An address before the convention of the American acceptance council at Detroit, June 9, 1919.Reprint.Mode of access ...
Wills, David C.   +1 more
core  

Pain, the self and persistence in problem solving [PDF]

open access: yes, 2012
Research has suggested that people are motivated to achieve their hopes for the future (hoped-for self) while trying to move away from that which they fear becoming (feared-for self).
Donaldson, Stephen Findlay
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Computer self-efficacy and computer anxiety: the effects on technology acceptance in implementing flipped learning approach [PDF]

open access: yes
The technology acceptance model was initially constructed to explain the behavioural intention in adopting and utilising an information system. The model has been widely used to investigate the level of technological innovation adoption, particularly in ...
Abd Rahman, Siti Fatimah   +1 more
core   +1 more source

Acceptance of aging among Japanese adults aged 20–89

open access: yesCogent Psychology
Objectives Acceptance of awareness of age-related change (AARC) is vital for mental health, yet the mechanisms underlying this process remain unclear.
Miho Nakajima, Hikari Kinjo
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Self-Attitude Parameters as Predictors of Psychological Well-Being in Students with Limited Health Capacities.

open access: yesСибСкрипт
Psychological well-being is a system of optimal psychological qualities and states manifested as life strategy and a system of personal attitude to the world and oneself. Self-attitude is an intrapersonal phenomenon of individual projections in the field
Oksana V. Zadorozhnaya   +1 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

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