Results 71 to 80 of about 1,568,820 (304)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Internet-Based Resources for Developing Listening

Studies in Self-Access Learning Journal, 2010
Developing listening skills comes “naturally” for some students, but with great difficulty for others. Acquiring listening skills can even be frustrating for some students.
Ene Peterson
doaj  

Tapping into the educational potential of Facebook : encouraging out-of-class peer collaboration in foreign language learning [PDF]

, 2015
Due to their social framework and often informal character, social network sites such as Facebook are believed to promote out-of-class learning by encouraging learners to participate in online peer collaboration.
Peeters, Ward
core  

Distance transactionnelle et centres de ressources en langues [PDF]

, 2010
National audienceThis article aims at establishing relationships between transactional distance theory, which articulates the variables of structure, dialog and learner autonomy, and the conception of a specific language learning system: a self-access ...
Guely, Eglantine
core   +4 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Principles and Procedures for Self-Access Materials

Studies in Self-Access Learning Journal, 2010
Like all language learning materials, self-access materials need to be developed from principles driven by what is known about the needs and wants of the target users. In my view, there should be a specification of universal principles, delivery specific
Brian Tomlinson
doaj  

Enhancing Self-Access in English Reading Comprehension Among Visually Impaired Students From Public Schools in Bogotá

Lenguaje, 2009
This article presents the findings of a research study carried out in 2007 and the first semester of 2008 with visually impaired students from public schools in Bogotá.
María Elena Perdomo Cerquera, Alonso Vergara Novoa   +1 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Listening to the Learner: A Qualitative Investigation of Motivation for Embracing or Avoiding the Use of Self-Access Centres

Studies in Self-Access Learning Journal, 2010
This paper reports on a follow-up study to Gillies (2007), in which a survey was conducted to investigate how tertiary-level Japanese EFL students understand and interpret their use or non-use of their institution’s self-access centre (SAC).
Hamish Gillies
doaj  

Editorial: Directions in Self-Access Learning [PDF]

Studies in Self-Access Learning Journal, 2014
This special issue accompanies the “Directions in Self-Access Learning” symposium held at Kanda University of International Studies in on October 19th, 2013. The purpose of the event was to explore past, present and future directions of the field of self-access learning and was aimed at newcomers and veterans alike.
openaire   +1 more source