Results 91 to 100 of about 7,196,003 (316)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Support for a reciprocal effects model of self-concept and academic achievement through a contrast of multidimensional and unidimensional approaches

, 2006
There is a longstanding debate in the self-concept literature surrounding the causal ordering of self-concept and academic achievement. Some researchers have argued that self-esteem has no positive impact upon performance (Baumeister, Campbell, Krueger &
Marsh, Herbert W., O'Mara, Alison J.
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The role of 5-HT1A and 5-HT1B receptors in MDMA self-administration

, 2016
Rationale: 3,4-methylenedioxymethamphetamine (MDMA) is a less efficacious reinforcer than other drugs of abuse. However, following repeated self-administration, responding increases for some animals and efficacy becomes comparable to other drugs of abuse.
Aronsen, Dane (11707085), Aronsen, Dane
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Investigating self-concept and health-related quality of life

, 2006
Health-related quality of life has been an important topic of research in diverse fields such as medicine, nursing, community service provision and psychology.
Dowson, Martin, Martin, Andrew J., Martinez, Carissa J.   +2 more
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Locomotor activity: A distinctive index in morphine self-administration in rats. [PDF]

, 2017
Self-administration of addictive drugs is a widely used tool for studying behavioral, neurobiological, and genetic factors in addiction. However, how locomotor activity is affected during self-administration of addictive drugs has not been extensively ...
Qingyao Kong, Kong, Qingyao, Jian-Jun Zhang, Zhang, Jian-Jun   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The measurement of multidimensional self-concept in adults with mild intellectual disability

, 2006
Although self-concept is now recognised as a multidimensional construct, unidimensional measurement is still common practise for adults with mild intellectual disabilities.
Craven, Rhonda, Martin, Andrew J., Dixon, Roselyn M.   +2 more
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Multifaceted self-concept of indigenous Australian secondary students : structure and relations to other academic variables

, 2006
In response to recent calls for the development of culturally relevant and applicable quantitative instruments for research into the educational disadvantages suffered by Indigenous Australian students, Bodkin-Andrews, Craven & Marsh (2005) analysed the ...
Craven, Rhonda, Bodkin-Andrews, Gawaian
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