Results 41 to 50 of about 977,715 (316)

Impact of tobacco smoke constituents on nicotine-seeking behavior in adolescent and adult male rats

Frontiers in Psychiatry, 2023
IntroductionGiven the rapid increase in teen vaping over recent years it is critical to understand mechanisms underlying addiction and relapse to tobacco use at this age.
Candice A. Gellner, Diana Carreño, James D. Belluzzi, Frances M. Leslie   +3 more
doaj   +1 more source

Recent updates on incubation of drug craving: a mini-review [PDF]

, 2015
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi, Bedi, Bienkowski, Chauvet, Chauvet, Conrad, Counotte, Fanous, Gawin, Grimm, Grimm, Guillem, Halbout, Hollander, Koya, Krasnova, Lee, Li, Li, Li, Loweth, Lu, Lu, Lu, Ma, Marchant, Neisewander, Pickens, Purgianto, Shalev, Shepard, Solinas, Sorge, Theberge, Thiel, Thiel, Tran-Nguyen, Uejima, Wang, Xi   +39 more
core   +1 more source

Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]

, 2014
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P, Babinska Z, Dusek L, FADDA, PAOLA, Fattore L., FRATTA, WALTER, Giugliano V, Kucerova J, Micale V, SCHERMA, MARIA, Sulcova A, ZANDA, MARY TRESA   +11 more
core   +1 more source

The reinforcing properties of ethanol are quantitatively enhanced in adulthood by peri-adolescent ethanol, but not saccharin, consumption in female alcohol-preferring (P) rats [PDF]

, 2015
Alcohol drinking during adolescence is associated in adulthood with heavier alcohol drinking and an increased rate of alcohol dependence. Past research in our laboratory has indicated that peri-adolescent ethanol consumption can enhance the acquisition ...
Bell, Richard L., Deehan Jr., Gerald A., Engleman, Eric A., Hauser, Sheketha R., McBride, William J., Murphy, James M., Rodd, Zachary A., Toalston, Jamie E.   +7 more
core   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Exercise decreases speedball self-administration [PDF]

Life Sciences, 2014
Epidemiological studies report that individuals who exercise are less likely to abuse drugs. Preclinical studies report that exercise, in the form of treadmill or wheel running, reliably decreases the self-administration of psychomotor stimulants and opioids.
Ryan T, Lacy, Justin C, Strickland, Mary K, Brophy, Maryam A, Witte, Mark A, Smith   +4 more
openaire   +2 more sources

Acute drug effects on habitual and non-habitual responding in crossed high alcohol preferring mice [PDF]

, 2018
RATIONALE: Drug reward plays a central role in acquiring drug-seeking behavior. However, subjects may continue using drugs despite negative consequences because self-administration becomes habitual, and divorced from outcome values. Although a history
Grahame, Nicholas J., Houck, Christa A.
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Alpha 1 Antitrypsin Therapy in Patients with Alpha 1 Antitrypsin Deficiency: Perspectives from a Registry Study and Practical Considerations for Self-Administration During the COVID-19 Pandemic

International Journal of COPD, 2021
Felix JF Herth,1 Robert A Sandhaus,2 Alice M Turner,3 Maria Sucena,4 Tobias Welte,5 Timm Greulich6 1Department of Pneumology and Critical Care Medicine, University of Heidelberg, Heidelberg, Germany; 2Division of Pulmonary, Critical Care and Sleep ...
Herth FJF, Sandhaus RA, Turner AM, Sucena M, Welte T, Greulich T   +5 more
doaj  

CB1 Receptor Antagonism Blocks Stress-Potentiated Reinstatement of Cocaine Seeking in Rats [PDF]

, 2015
Rationale Under some conditions, stress, rather than directly triggering cocaine seeking, potentiates reinstatement to other stimuli, including a subthreshold cocaine dose.
Baker, David A., Doncheck, Elizabeth M., Ganzman, Geoffrey S., Hillard, Cecilia J., Mantsch, John R., McReynolds, Jayme R., Vranjkovic, Oliver   +6 more
core   +2 more sources