Results 61 to 70 of about 7,267,221 (342)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The Effects of Excitatory and Inhibitory Social Cues on Cocaine-Seeking Behavior
Frontiers in Behavioral Neuroscience, 2016 Social partners influence the likelihood of using drugs, developing a substance use disorder, and relapse to drug use after a period of abstinence. Preclinical studies report that social cues influence the acquisition of cocaine use, the escalation of ...
Mark Andrew Smith +2 more
doaj +1 more source
The Effects of Cocaine on Different Redox Forms of Cysteine and Homocysteine, and on Labile, Reduced Sulfur in the Rat Plasma Following Active versus Passive Drug Injections [PDF]
, 2013 Received: 28 November 2012 / Revised: 19 April 2013 / Accepted: 6 May 2013 / Published online: 16 May 2013 The Author(s) 2013. This article is published with open access at Springerlink.comThe aim of the present studies was to evaluate cocaine ...
A Madayag +80 more
core +2 more sources
FEBS Letters, EarlyView.This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk +3 more
wiley +1 more source
Involvement of the Cuneate Nucleus in the Acupuncture Inhibition of Drug-Seeking Behaviors
Frontiers in Neuroscience, 2019 Our previous studies have shown that acupuncture suppresses addictive behaviors induced by drugs of abuse, including cocaine, morphine and ethanol, by modulating GABA neurons in the ventral tegmental area (VTA) and dopamine (DA) release in the nucleus ...
Suchan Chang +10 more
doaj +1 more source
Case report: Self-administration of alpha-1 antitrypsin therapy: a report of two cases
Frontiers in Pharmacology, 2023 Intravenous augmentation therapy with human alpha-1 proteinase inhibitor for the management of respiratory disease is recommended for people with alpha-1 antitrypsin deficiency (AATD) who are nonsmokers or former smokers.
Ana M. Escribano Dueñas +3 more
doaj +1 more source
Drug Predictive Cues Activate Aversion-Sensitive Striatal Neurons That Encode Drug Seeking [PDF]
, 2015 Drug-associated cues have profound effects on an addict’s emotional state and drug-seeking behavior. Although this influence must involve the motivational neural system that initiates and encodes the drug-seeking act, surprisingly little is known about ...
Dupont, Matthew J. +5 more
core +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2018 Substance abuse and depression are common psychiatric disorders with a high rate of comorbidity. Both conditions affect differently men and women and preclinical research has showed many sex differences in drug addiction and depression.
Jana Ruda-Kucerova +6 more
doaj +1 more source
Formulation and Evaluation of Self-Emulsifying Drug Delivery Systems of Larotaxel for Oral Administration [PDF]
, 2023 Wang Ming-li +7 more
openalex +1 more source