Results 41 to 50 of about 45,169 (258)
Advanced Science, EarlyView.SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao +15 more
wiley +1 more source
NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment
Advanced Science, EarlyView.NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang +8 more
wiley +1 more source
Self-archiving in digital repositories: the roots of the past and the data of the present
Cybrarians Journal, 2014 This research deals with the topic of self-archiving, and in particular the practice of digital repositories in terms of definition, historical roots, goals, strategies, advantages, with reference to the most important initiatives and statements that ...
Wessam Benghida
doaj +1 more source
Self-archive unto others as ye would have them self-archive unto you [PDF]
Journal of Science Communication, 2003 Scholars and scientists do research to create new knowledge so that other scholars and scientists can use it to create still more new knowledge and to apply it to improving people's lives. They are paid to do research, but not to report their research: that they do for free, because it is not royalty-revenue from their research papers but their ...
openaire +3 more sources
Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis
Advanced Science, EarlyView.ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu +26 more
wiley +1 more source
Self-Archiving with Ease in an Institutional Repository: Microinteractions and the User Experience
Information Technology and Libraries, 2015 Details matter, especially when they can influence whether or not users engage with a new digital initiative that relies heavily on their support. During the recent development of MacEwan University’s institutional repository, the librarians leading the ...
Sonya Betz, Robyn Hall
doaj +1 more source
stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics
Advanced Science, EarlyView.stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang +3 more
wiley +1 more source
Developing strategies to ensure compliance with funders’ open access policies
Insights: The UKSG Journal, 2015 Funding bodies for higher education institutions (HEIs) in the United Kingdom (UK) have recently introduced policies with a strong focus on open access (OA).
Nancy Pontika, Dace Rozenberga
doaj +1 more source
, 2009 Christian Zimmermann, About self-archiving your research, The RePEc Blog, May 15, 2009.
openaire +1 more source
NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Advanced Science, EarlyView.Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source